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Receptor

Search Result - 1

HMRbase accession number	20004
Swiss-prot Accession number	Q9NYK7 (Sequence in FASTA format)
Description	CCK-B/gastrin receptor.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	516 Amino acids
Molecular weight	55857
Domain Name	N/A
References	1  PubMed abstract 10913157 2  PubMed abstract 7887934
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	20015
Swiss-prot Accession number	Q8IV17 (Sequence in FASTA format)
Description	Secretin receptor.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	440 Amino acids
Molecular weight	50221
Domain Name	7tm_2  HRM
References	1  PubMed abstract 12477932 2   Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Hormone	P09683   Detail in HMRbase
Gene ID	6344
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 3

HMRbase accession number	20017
Swiss-prot Accession number	O95718 (Sequence in FASTA format)
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR-beta) (Estrogen receptor-like 2) (ERR beta-2).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	500 Amino acids
Molecular weight	55619
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 10072763 2  PubMed abstract 12508121
Hormone	N/A
Gene ID	2103
PDB ID	1LO1
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 4

HMRbase accession number	20032
Swiss-prot Accession number	Q14246 (Sequence in FASTA format)
Description	EGF-like module-containing mucin-like hormone receptor-like 1precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains. Contains 1 GPS domain.
Tissue Specificity	Wide expression; increased levels in peripheral blood mononuclear cells.
Post translational modification	N/A
Function	Could be involved in cell-cell interactions.
Protein Length	886 Amino acids
Molecular weight	97625
Domain Name	7tm_2  EGF_CA  GPS  EGF
References	1  PubMed abstract 7601460 2   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 15489334
Hormone	N/A
Gene ID	2015
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 5

HMRbase accession number	20036
Swiss-prot Accession number	Q9UHX3 (Sequence in FASTA format)
Description	EGF-like module-containing mucin-like hormone receptor-like 2precursor (EGF-like module EMR2) (CD312 antigen).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 5 EGF-like domains. Contains 1 GPS domain.
Tissue Specificity	Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested.
Post translational modification	Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.
Function	Receptor probably involved in cell attachment.
Protein Length	823 Amino acids
Molecular weight	90472
Domain Name	EGF_CA  7tm_2  GPS  EGF
References	1  PubMed abstract 10903844 2   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 15057824 4  PubMed abstract 12860403 5  PubMed abstract 12829604 6  PubMed abstract 11994511
Hormone	N/A
Gene ID	30817
PDB ID	2BO2   2BOU   2BOX
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 6

HMRbase accession number	20038
Swiss-prot Accession number	Q9BY15 (Sequence in FASTA format)
Description	EGF-like module-containing mucin-like hormone receptor-like 3precursor (EGF-like module-containing mucin-like receptor EMR3).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein. Subunit alpha: Secreted protein; extracellular space. Note=A soluble form is also detected (alpha subunit)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 2 EGF-like domains. Contains 1 GPS domain.
Tissue Specificity	Displays a predominantly leukocyte-restricted expression, with highest levels in neutrophils, monocytes and macrophages.
Post translational modification	Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit (By similarity).
Function	Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils.
Protein Length	652 Amino acids
Molecular weight	72593
Domain Name	7tm_2  GPS  EGF_CA
References	1  PubMed abstract 11279179 2  PubMed abstract 12975309 3  PubMed abstract 17081983
Hormone	N/A
Gene ID	84658
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 7

HMRbase accession number	20039
Swiss-prot Accession number	Q86SQ3 (Sequence in FASTA format)
Description	EGF-like module-containing mucin-like hormone receptor-like 4precursor (G-protein coupled receptor 127) (Fragment).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 2 EGF-like domains. Contains 1 GPS domain.
Tissue Specificity	N/A
Post translational modification	Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit (By similarity).
Function	Could mediated the cellular interaction between myeloid cells and B-cells (By similarity).
Protein Length	457 Amino acids
Molecular weight	50903
Domain Name	7tm_2  GPS  EGF_CA
References	1  PubMed abstract 12565841 2  PubMed abstract 12731063 3  PubMed abstract 12679517
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 8

HMRbase accession number	20041
Swiss-prot Accession number	P11474 (Sequence in FASTA format)
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter.
Protein Length	519 Amino acids
Molecular weight	55440
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 3267207 2  PubMed abstract 8621448 3  PubMed abstract 8224847 4  PubMed abstract 9271417 5  PubMed abstract 15302935
Hormone	N/A
Gene ID	2101
PDB ID	1XB7   2PJL   3D24
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 9

HMRbase accession number	20047
Swiss-prot Accession number	Q92847 (Sequence in FASTA format)
Description	Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasingpeptide receptor) (GHRP) (Ghrelin receptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Pituitary and hypothalamus.
Post translational modification	N/A
Function	Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).
Protein Length	366 Amino acids
Molecular weight	41329
Domain Name	7tm_1
References	1  PubMed abstract 8688086 2  PubMed abstract 11356716 3   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15489334 5  PubMed abstract 11322507 6  PubMed abstract 10604470
Hormone	N/A
Gene ID	2693
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 10

HMRbase accession number	20070
Swiss-prot Accession number	Q9Y618 (Sequence in FASTA format)
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator ofretinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-,retinoic-acid-receptor-associated corepressor) (T3 receptor-associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the N-CoR nuclear receptor corepressors family. Contains 2 SANT domains.
Tissue Specificity	Ubiquitous. High levels of expression are detected in lung, spleen and brain.
Post translational modification	N/A
Function	Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription.
Protein Length	2517 Amino acids
Molecular weight	274034
Domain Name	N/A
References	1  PubMed abstract 10077563 2  PubMed abstract 10097068 3  PubMed abstract 7566127 4  PubMed abstract 8813722 5  PubMed abstract 9225980 6  PubMed abstract 11331609 7  PubMed abstract 10809664 8  PubMed abstract 10944117 9  PubMed abstract 11931768 10  PubMed abstract 11739383 11  PubMed abstract 15302935 12  PubMed abstract 17081983
Hormone	N/A
Gene ID	N/A
PDB ID	1KKQ   1R2B   1XC5   2ODD
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 11

HMRbase accession number	20156
Swiss-prot Accession number	Q14995 (Sequence in FASTA format)
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclearhormone receptor BD73).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Binds to the sequences 5'-AATGTAGGTCA-3' and 5'- ATAACTAGGTCA-3'. Acts as a potent competitive repressor of ROR alpha function (By similarity).
Protein Length	579 Amino acids
Molecular weight	64643
Domain Name	zf-C4  Hormone_recep
References	1   Kamizono A., Shuichiro K., Kohei U.; "Isolation of a novel member of the thyroid/steroid hormone receptorsuperfamily from human osteoblastic osteosarcoma HOS cell."; Submitted (JUL-1993) to the EMBL/GenBank/DDBJ databases. 2  PubMed abstract 7997240 3  PubMed abstract 15489334 4  PubMed abstract 11113208
Hormone	N/A
Gene ID	9975
PDB ID	2V0V   2V7C   3CQV
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 12

HMRbase accession number	20158
Swiss-prot Accession number	Q92570 (Sequence in FASTA format)
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1)(Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphanreceptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	High expression of isoform alpha in skeletal muscle. High expression of isoform beta in skeletal muscle and low expression in fetal brain and placenta.
Post translational modification	N/A
Function	Binds to the B1A response-element.
Protein Length	626 Amino acids
Molecular weight	68230
Domain Name	zf-C4  Hormone_recep
References	1  PubMed abstract 8809112 2  PubMed abstract 8614405 3  PubMed abstract 8570200 4  PubMed abstract 8634690 5  PubMed abstract 15164053 6  PubMed abstract 9573341
Hormone	N/A
Gene ID	8013
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 13

HMRbase accession number	20162
Swiss-prot Accession number	P28069 (Sequence in FASTA format)
Description	Pituitary-specific positive transcription factor 1 (Pit-1) (Growthhormone factor 1) (GHF-1).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the POU transcription factor family. Class- 1 subfamily. Contains 1 homeobox DNA-binding domain. Contains 1 POU-specific domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'- TAAAT-3'.
Protein Length	291 Amino acids
Molecular weight	32912
Domain Name	Pou  Homeobox
References	1  PubMed abstract 1956794 2  PubMed abstract 1370379 3   Tatsumi K., Notomi T., Irie Y., Endo Y., Onogi S., Amino N., Miyai K.; "The structure and the chromosomal location of the human PIT1 gene."; Submitted (AUG-1992) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 1487156 5  PubMed abstract 7721104 6  PubMed abstract 8346040 7  PubMed abstract 1472057 8  PubMed abstract 1509263 9  PubMed abstract 1509262 10  PubMed abstract 8768831 11  PubMed abstract 9485179 12  PubMed abstract 9626142 13  PubMed abstract 11297581
Hormone	N/A
Gene ID	5449
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 14

HMRbase accession number	20163
Swiss-prot Accession number	Q03181 (Sequence in FASTA format)
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR-beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Ubiquitous with maximal levels in placenta and skeletal muscle.
Post translational modification	N/A
Function	Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Decreases expression of NPC1L1 once activated by a ligand.
Protein Length	441 Amino acids
Molecular weight	49903
Domain Name	zf-C4  Hormone_recep
References	1  PubMed abstract 1333051 2  PubMed abstract 10851270 3   Livingston R.J., Rieder M.J., Chung M.-W., Ritchie T.K., Olson A.N.,Nguyen C.P., Nguyen D.A., Poel C.L., Robertson P.D., Schackwitz W.S.,Sherwood J.K., Sherwood A.M., Leithauser B.J., Nickerson D.A.; "NIEHS-SNPs, environmental genome project, NIEHS ES15478, Departmentof Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 14574404 5  PubMed abstract 15489334 6   Aoto T., Ishizuka M., Kazusaka A., Fujita S.; "PPAR-delta 5'-complete cDNA fragment."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 15604518
Hormone	Detail in HMRbase
Gene ID	5467
PDB ID	1GWX   1Y0S   2AWH   2B50   2BAW   2ENV   2GWX   2J14   2Q5G   3D5F   3GWX
Drugpedia	wiki
Comments

Search Result - 15

HMRbase accession number	20167
Swiss-prot Accession number	P49190 (Sequence in FASTA format)
Description	Parathyroid hormone receptor precursor (PTH2 receptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	Expressed abundantly in brain and pancreas. Also expressed in the testis.
Post translational modification	N/A
Function	This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTHR2 may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTHR2 presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity).
Protein Length	550 Amino acids
Molecular weight	62236
Domain Name	7tm_2  HRM
References	1  PubMed abstract 7797535 2   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 15489334 4  PubMed abstract 8921382 5  PubMed abstract 11861531
Hormone	N/A
Gene ID	5746
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 16

HMRbase accession number	20173
Swiss-prot Accession number	P04278 (Sequence in FASTA format)
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-bindingprotein) (SBP) (Testis-specific androgen-binding protein) (ABP)(Testosterone-estrogen-binding globulin) (Testosterone-estradiol-binding globulin) (TeBG).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Secreted protein (By similarity). Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis (By similarity)
Developmental Stage	N/A
Similarity	Contains 2 laminin G-like domains.
Tissue Specificity	Isoforms 1 and 2 are present in liver and testis.
Post translational modification	N/A
Function	Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
Protein Length	402 Amino acids
Molecular weight	43779
Domain Name	Laminin_G_1  Laminin_G_2
References	1  PubMed abstract 2587256 2  PubMed abstract 2608061 3  PubMed abstract 15489334 4  PubMed abstract 3569533 5  PubMed abstract 2956126 6  PubMed abstract 2956125 7  PubMed abstract 3702459 8  PubMed abstract 3542030 9  PubMed abstract 16335952 10  PubMed abstract 1400872 11  PubMed abstract 10675319 12  PubMed abstract 12065592 13  PubMed abstract 7714097 14  PubMed abstract 10391209 15   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999).
Hormone	N/A
Gene ID	6462
PDB ID	1D2S   1F5F   1KDK   1KDM   1LHN   1LHO   1LHU   1LHV   1LHW
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 17

HMRbase accession number	20180
Swiss-prot Accession number	Q13285 (Sequence in FASTA format)
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein)(Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR5 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P-450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the Muellerian inhibiting substance (AMH) gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1/FTZF1. The SFPQ-NONO- NR5A1/SF-1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3.
Protein Length	461 Amino acids
Molecular weight	51636
Domain Name	zf-C4  Hormone_recep
References	1   Santa Barbara P., Desclozeaux M., Boizet B., Bonneaud N., Laudet V.,Poulat F., Berta P.; "Cloning and characterization of the human steroidogenic factor 1 (SF-1) cDNA."; Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases. 2  PubMed abstract 8806624 3  PubMed abstract 15489334 4   Yeh J.R., Chung B.C.; "Human SF1 genomic segment."; Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 11897684 6  PubMed abstract 15707893 7  PubMed abstract 15897460 8  PubMed abstract 10369247 9  PubMed abstract 11038323 10  PubMed abstract 11932325
Hormone	N/A
Gene ID	2516
PDB ID	1YOW   1ZDT
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 18

HMRbase accession number	20195
Swiss-prot Accession number	P10827 (Sequence in FASTA format)
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7)(EAR7).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Nuclear hormone receptor. High affinity receptor for triiodothyronine.
Protein Length	490 Amino acids
Molecular weight	54816
Domain Name	zf-C4  Hormone_recep
References	1  PubMed abstract 1850510 2  PubMed abstract 2539258 3  PubMed abstract 3357890 4  PubMed abstract 3684612 5  PubMed abstract 2464749 6  PubMed abstract 15489334 7  PubMed abstract 3672126 8   Liu C., Li L., Liu B., Zang X.; Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases. 9  PubMed abstract 9267036 10  PubMed abstract 9627117 11  PubMed abstract 10567404
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	7067
PDB ID	1NAV   2H79
Drugpedia	wiki
Comments

Search Result - 19

HMRbase accession number	20204
Swiss-prot Accession number	P10828 (Sequence in FASTA format)
Description	Thyroid hormone receptor beta-1.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	High affinity receptor for triiodothyronine.
Protein Length	461 Amino acids
Molecular weight	52788
Domain Name	zf-C4  Hormone_recep
References	1  PubMed abstract 2879243 2  PubMed abstract 3034496 3  PubMed abstract 1973914 4  PubMed abstract 15489334 5  PubMed abstract 11971969 6  PubMed abstract 7746322 7  PubMed abstract 1324420 8  PubMed abstract 8381821 9  PubMed abstract 8514853 10  PubMed abstract 1661299 11  PubMed abstract 1314846 12  PubMed abstract 1653889 13  PubMed abstract 1846005 14  PubMed abstract 1563081 15  PubMed abstract 2510172 16  PubMed abstract 1587388 17  PubMed abstract 8175986 18  PubMed abstract 2153155 19  PubMed abstract 1619012 20  PubMed abstract 7833659 21  PubMed abstract 8664910 22  PubMed abstract 8889584 23  PubMed abstract 10660344
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	7068
PDB ID	1BSX   1N46   1NAX   1NQ0   1NQ1   1NQ2   1NUO   1Q4X   1R6G   1XZX   1Y0X   2H6W   2J4A   2NLL   2PIN
Drugpedia	wiki
Comments

Search Result - 20

HMRbase accession number	20208
Swiss-prot Accession number	P37243 (Sequence in FASTA format)
Description	Thyroid hormone receptor beta-2.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	High affinity receptor for triiodothyronine.
Protein Length	476 Amino acids
Molecular weight	54356
Domain Name	zf-C4  Hormone_recep
References	1   Damm K., Berning B.; Submitted (AUG-1993) to the EMBL/GenBank/DDBJ databases. 2  PubMed abstract 2879243 3  PubMed abstract 11971969
Hormone	Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 21

HMRbase accession number	20221
Swiss-prot Accession number	P47898 (Sequence in FASTA format)
Description	5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5-HT-5).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.
Protein Length	357 Amino acids
Molecular weight	40255
Domain Name	7tm_1
References	1  PubMed abstract 7988681 2   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 15489334 4  PubMed abstract 7988681 5   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 15489334
Hormone	Detail in HMRbase
Gene ID	3361
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 22

HMRbase accession number	20226
Swiss-prot Accession number	Q7M4L8 (Sequence in FASTA format)
Description	Melanocortin receptor 1.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34749
Domain Name	N/A
References	1  PubMed abstract 8060302
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 23

HMRbase accession number	20230
Swiss-prot Accession number	Q5VXR2 (Sequence in FASTA format)
Description	Adrenergic, alpha-1D-, receptor.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium (By similarity).
Protein Length	572 Amino acids
Molecular weight	60463
Domain Name	7tm_1
References	1   Beasley H.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 24

HMRbase accession number	20262
Swiss-prot Accession number	O43192 (Sequence in FASTA format)
Description	Vasopressin receptor type 2.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	309 Amino acids
Molecular weight	33743
Domain Name	7tm_1
References	1  PubMed abstract 1534149 2  PubMed abstract 8735975 3  PubMed abstract 1415251 4   Du J., Fay M.J., Yu X., North W.G.; "A truncated human vasopressin receptor type 2 produced by alternativesplicing intron 2 in small-cellcarcinoma of the lung."; Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 25

HMRbase accession number	20263
Swiss-prot Accession number	Q3S2J4 (Sequence in FASTA format)
Description	Arginine vasopressin receptor 1.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	418 Amino acids
Molecular weight	46855
Domain Name	7tm_1  DUF1856
References	1   Campbell K.K., Baysdorfer C., Antonini S.R., Lacroix A.; "V1-Vasopressin Receptor Sequence and Expression in Adrenal Cushing'sSyndrome with Aberrant Response to Vasopressin."; Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 26

HMRbase accession number	20291
Swiss-prot Accession number	P08908 (Sequence in FASTA format)
Description	5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A) (G-21).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Protein Length	422 Amino acids
Molecular weight	46107
Domain Name	7tm_1
References	1  PubMed abstract 3041227 2   Saltzman A.G., Morse B., Felder S.; Submitted (FEB-1991) to the EMBL/GenBank/DDBJ databases. 3   Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. 4   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 15489334 6  PubMed abstract 1766875 7  PubMed abstract 8393041 8  PubMed abstract 3138543 9  PubMed abstract 17203973 10  PubMed abstract 7755630 11  PubMed abstract 9754630
Hormone	N/A
Gene ID	3350
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 27

HMRbase accession number	20303
Swiss-prot Accession number	P28222 (Sequence in FASTA format)
Description	5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B) (5-HT-1D-beta) (Serotonin 1D beta receptor) (S12).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	Phosphorylated. Desensitization of the receptor may be mediated by its phosphorylation. Palmitoylated.
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Protein Length	390 Amino acids
Molecular weight	43568
Domain Name	7tm_1
References	1  PubMed abstract 1565658 2  PubMed abstract 1351684 3  PubMed abstract 1610347 4  PubMed abstract 1315531 5  PubMed abstract 1559993 6  PubMed abstract 1328844 7  PubMed abstract 1348246 8   Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. 9   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 10  PubMed abstract 14574404 11  PubMed abstract 15489334 12  PubMed abstract 8218242 13  PubMed abstract 7802650 14  PubMed abstract 1565658 15  PubMed abstract 1351684 16  PubMed abstract 1610347 17  PubMed abstract 1315531 18  PubMed abstract 1559993 19  PubMed abstract 1328844 20  PubMed abstract 1348246 21   Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. 22   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 23  PubMed abstract 14574404 24  PubMed abstract 15489334 25  PubMed abstract 8218242 26  PubMed abstract 7802650
Hormone	N/A
Gene ID	3351
PDB ID	2G1X
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 28

HMRbase accession number	20313
Swiss-prot Accession number	P28221 (Sequence in FASTA format)
Description	5-hydroxytryptamine 1D receptor (5-HT-1D) (Serotonin receptor 1D) (5-HT-1D-alpha).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Protein Length	377 Amino acids
Molecular weight	41907
Domain Name	7tm_1
References	1  PubMed abstract 1652050 2  PubMed abstract 1565658 3   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 4   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 16710414 6  PubMed abstract 15489334 7  PubMed abstract 10391209 8   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999).
Hormone	N/A
Gene ID	3352
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 29

HMRbase accession number	20317
Swiss-prot Accession number	P28566 (Sequence in FASTA format)
Description	5-hydroxytryptamine 1E receptor (5-HT-1E) (Serotonin receptor 1E) (5-HT1E) (S31).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Protein Length	365 Amino acids
Molecular weight	41682
Domain Name	7tm_1
References	1  PubMed abstract 1608964 2  PubMed abstract 1733778 3  PubMed abstract 1513320 4   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 14574404 6  PubMed abstract 15489334 7   Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. 8  PubMed abstract 10391209 9   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999).
Hormone	N/A
Gene ID	3354
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 30

HMRbase accession number	20319
Swiss-prot Accession number	P30939 (Sequence in FASTA format)
Description	5-hydroxytryptamine 1F receptor (5-HT-1F) (Serotonin receptor 1F).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Protein Length	366 Amino acids
Molecular weight	41709
Domain Name	7tm_1
References	1  PubMed abstract 8384716 2  PubMed abstract 8380639 3   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15489334
Hormone	N/A
Gene ID	3355
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 31

HMRbase accession number	20327
Swiss-prot Accession number	P28223 (Sequence in FASTA format)
Description	5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Protein Length	471 Amino acids
Molecular weight	52603
Domain Name	7tm_1
References	1  PubMed abstract 1722404 2  PubMed abstract 1323014 3  PubMed abstract 8035173 4   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 15057823 6  PubMed abstract 15489334 7   Tritch R.J., Robinson D.L., Sahagan B.G., Horlick R.A.; "Cloning and nucleotide sequence of the human(5HT) type 2 receptor."; Submitted (MAY-1992) to the EMBL/GenBank/DDBJ databases. 8  PubMed abstract 1330647 9  PubMed abstract 11150294 10  PubMed abstract 14988405 11  PubMed abstract 8655141 12  PubMed abstract 10581480 13  PubMed abstract 10391209 14   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 15  PubMed abstract 1722404 16  PubMed abstract 1323014 17  PubMed abstract 8035173 18   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 19  PubMed abstract 15057823 20  PubMed abstract 15489334 21   Tritch R.J., Robinson D.L., Sahagan B.G., Horlick R.A.; "Cloning and nucleotide sequence of the human(5HT) type 2 receptor."; Submitted (MAY-1992) to the EMBL/GenBank/DDBJ databases. 22  PubMed abstract 1330647 23  PubMed abstract 11150294 24  PubMed abstract 14988405 25  PubMed abstract 8655141 26  PubMed abstract 10581480 27  PubMed abstract 10391209 28   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999).
Hormone	Detail in HMRbase
Gene ID	3356
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 32

HMRbase accession number	20334
Swiss-prot Accession number	P41595 (Sequence in FASTA format)
Description	5-hydroxytryptamine 2B receptor (5-HT-2B) (Serotonin receptor 2B).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Detected in most peripheral organs. Only low expression levels were found in the brain.
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein Length	481 Amino acids
Molecular weight	54298
Domain Name	7tm_1
References	1  PubMed abstract 8143856 2  PubMed abstract 7926008 3  PubMed abstract 8078486 4  PubMed abstract 10722792 5   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 15815621 7  PubMed abstract 15489334 8  PubMed abstract 11150294 9  PubMed abstract 8143856 10  PubMed abstract 7926008 11  PubMed abstract 8078486 12  PubMed abstract 10722792 13   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. 14  PubMed abstract 15815621 15  PubMed abstract 15489334 16  PubMed abstract 11150294 17  PubMed abstract 8143856 18  PubMed abstract 7926008 19  PubMed abstract 8078486 20  PubMed abstract 10722792 21   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. 22  PubMed abstract 15815621 23  PubMed abstract 15489334 24  PubMed abstract 11150294
Hormone	N/A
Gene ID	3357
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 33

HMRbase accession number	20338
Swiss-prot Accession number	P28335 (Sequence in FASTA format)
Description	5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) (5-HT2C) (5-HTR2C) (5HT-1C).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N-glycosylated.
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein Length	458 Amino acids
Molecular weight	51821
Domain Name	7tm_1
References	1  PubMed abstract 1722404 2  PubMed abstract 7895773 3  PubMed abstract 8812491 4  PubMed abstract 9928237 5   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 15772651 7  PubMed abstract 15489334 8  PubMed abstract 11150294 9  PubMed abstract 7557992 10  PubMed abstract 10206230 11  PubMed abstract 10581480 12  PubMed abstract 10391209 13   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 14  PubMed abstract 1722404 15  PubMed abstract 7895773 16  PubMed abstract 8812491 17  PubMed abstract 9928237 18   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 19  PubMed abstract 15772651 20  PubMed abstract 15489334 21  PubMed abstract 11150294 22  PubMed abstract 7557992 23  PubMed abstract 10206230 24  PubMed abstract 10581480 25  PubMed abstract 10391209 26   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999).
Hormone	Detail in HMRbase
Gene ID	3358
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 34

HMRbase accession number	20343
Swiss-prot Accession number	Q13639 (Sequence in FASTA format)
Description	5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5-HT4).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Isoform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle.
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
Protein Length	388 Amino acids
Molecular weight	43761
Domain Name	7tm_1
References	1  PubMed abstract 9603189 2   Van den Wyngaert I., Gommeren W., Jurzak M., Verhasselt P., Gordon R.,Leysen J., Luyten W., Bender E.; "Cloning and expression of 5-HT4 receptor species and splicevariants."; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 9351641 4  PubMed abstract 10220570 5   Vilaro M.T., Domenech T., Palacios J.M., Mengod G.; "Cloning and characterization of multiple human 5-HT4 receptorvariants including a novel variant that lacks the alternativelyspliced C-terminal exon."; Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 15489334 7  PubMed abstract 10646498 8  PubMed abstract 7656980
Hormone	Detail in HMRbase
Gene ID	3360
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 35

HMRbase accession number	20350
Swiss-prot Accession number	P50406 (Sequence in FASTA format)
Description	5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed in several human brain regions, most prominently in the caudate nucleus.
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.
Protein Length	440 Amino acids
Molecular weight	46954
Domain Name	7tm_1
References	1  PubMed abstract 8522988 2   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 15489334 4  PubMed abstract 7656980 5  PubMed abstract 16094384
Hormone	N/A
Gene ID	3362
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 36

HMRbase accession number	20355
Swiss-prot Accession number	P34969 (Sequence in FASTA format)
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT-X) (5HT7).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels, and isoform D is a minor isoform.
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
Protein Length	479 Amino acids
Molecular weight	53555
Domain Name	7tm_1
References	1  PubMed abstract 9084407 2  PubMed abstract 8226867 3   King M.M., Aronstam R.S., Sharma S.V.; "Isolation of cDNA coding for 5-hydroxytryptamine receptor 7,transcript variant b (HTR7B)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15489334 5  PubMed abstract 9154233
Hormone	N/A
Gene ID	3363
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 37

HMRbase accession number	20383
Swiss-prot Accession number	Q546Q1 (Sequence in FASTA format)
Description	5-hydroxytryptamine4 receptor (5-hydroxytryptamine (Serotonin)receptor 4) (Serotonin receptor 5-HT4).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity).
Protein Length	388 Amino acids
Molecular weight	43761
Domain Name	7tm_1
References	1  PubMed abstract 11750916 2  PubMed abstract 12477932 3   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. 4   Syversveen T., Bach T., Kvingedal A.M., Krobert K.A., Kaumann A.J.,Levy F.O.; "Molecular cloning of the human serotonin receptor 5-HT4(b) andpharmacological comparison with the cloned human 5-HT4(a) receptor."; Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	3360
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 38

HMRbase accession number	20385
Swiss-prot Accession number	Q5TGZ1 (Sequence in FASTA format)
Description	5-hydroxytryptamine (Serotonin) receptor 6.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	440 Amino acids
Molecular weight	46954
Domain Name	7tm_1
References	1   Lad H.; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 39

HMRbase accession number	20387
Swiss-prot Accession number	Q5VX01 (Sequence in FASTA format)
Description	5-hydroxytryptamine (Serotonin) receptor 7 (Adenylate cyclase-coupled).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	432 Amino acids
Molecular weight	47984
Domain Name	7tm_1
References	1   Whitehead S.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 40

HMRbase accession number	20388
Swiss-prot Accession number	Q5VX02 (Sequence in FASTA format)
Description	5-hydroxytryptamine (Serotonin) receptor 7 (Adenylate cyclase-coupled).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	445 Amino acids
Molecular weight	49488
Domain Name	7tm_1
References	1   Whitehead S.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	3363
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 41

HMRbase accession number	20389
Swiss-prot Accession number	Q5VX03 (Sequence in FASTA format)
Description	5-hydroxytryptamine (Serotonin) receptor 7 (Adenylate cyclase-coupled).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	479 Amino acids
Molecular weight	53555
Domain Name	7tm_1
References	1   Whitehead S.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	3363
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 42

HMRbase accession number	20390
Swiss-prot Accession number	Q5VX04 (Sequence in FASTA format)
Description	5-hydroxytryptamine (Serotonin) receptor 7 (Adenylate cyclase-coupled).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	479 Amino acids
Molecular weight	53567
Domain Name	7tm_1
References	1   Whitehead S.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 43

HMRbase accession number	20391
Swiss-prot Accession number	Q5ZGX3 (Sequence in FASTA format)
Description	5-hydroxytryptamine receptor 1A.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity).
Protein Length	422 Amino acids
Molecular weight	46107
Domain Name	7tm_1
References	1   Patra A.K., Saravanan T., Aarthi R., Chugh A.; "Amplification and cloning of serotonin receptor, 5-hydroxy tryptaminereceptor 1A from Indian blood."; Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. 2   Patra S.K.; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	3350
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 44

HMRbase accession number	20393
Swiss-prot Accession number	Q684M0 (Sequence in FASTA format)
Description	5-hydroxytryptamine 4 receptor isoform g2 (Serotonin receptor 5- HT4).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity).
Protein Length	378 Amino acids
Molecular weight	42746
Domain Name	7tm_1
References	1  PubMed abstract 15118808
Hormone	N/A
Gene ID	3360
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 45

HMRbase accession number	20401
Swiss-prot Accession number	Q712M9 (Sequence in FASTA format)
Description	Serotonin receptor 5-HT4.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity).
Protein Length	428 Amino acids
Molecular weight	48255
Domain Name	7tm_1
References	1  PubMed abstract 15118808
Hormone	N/A
Gene ID	3360
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 46

HMRbase accession number	20413
Swiss-prot Accession number	Q8IXH9 (Sequence in FASTA format)
Description	5-hydroxytryptamine 4 receptor subunit b.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity).
Protein Length	388 Amino acids
Molecular weight	43789
Domain Name	7tm_1
References	1   Bruss M., Bonisch H.; "Molecular cloning and pharmacological characterization of human 5-HT4-like receptors."; Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases. 2   Bruess M.; Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 47

HMRbase accession number	20423
Swiss-prot Accession number	Q16144 (Sequence in FASTA format)
Description	Cholecystokinin B receptor.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	447 Amino acids
Molecular weight	48418
Domain Name	7tm_1
References	1  PubMed abstract 8185170 2  PubMed abstract 7887934
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 48

HMRbase accession number	20424
Swiss-prot Accession number	Q92492 (Sequence in FASTA format)
Description	Cholecystokinin-B receptor/gastrin receptor.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	447 Amino acids
Molecular weight	48419
Domain Name	7tm_1
References	1  PubMed abstract 8349705 2  PubMed abstract 7848914 3  PubMed abstract 8222757 4  PubMed abstract 7887934
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 49

HMRbase accession number	20425
Swiss-prot Accession number	Q96LC6 (Sequence in FASTA format)
Description	CCK-B/gastrin receptor variant (Cholecystokinin-C receptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	516 Amino acids
Molecular weight	55841
Domain Name	7tm_1
References	1   Schmitz F., Schrader H., Stueber E., Schmidt W.E.; "Identification of CCK-B/gastrin receptor splice variants in humanperipheral blood mononuclear cells."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases. 2  PubMed abstract 7887934 3  PubMed abstract 12429993
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 50

HMRbase accession number	20426
Swiss-prot Accession number	P41968 (Sequence in FASTA format)
Description	Melanocortin receptor 3 (MC3-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Brain, placental, and gut tissues.
Post translational modification	N/A
Function	Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase.
Protein Length	360 Amino acids
Molecular weight	40073
Domain Name	7tm_1
References	1  PubMed abstract 8463333 2   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 11780052 4  PubMed abstract 15489334 5  PubMed abstract 8463333 6   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 11780052 8  PubMed abstract 15489334
Hormone	N/A
Gene ID	4159
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 51

HMRbase accession number	20430
Swiss-prot Accession number	P32245 (Sequence in FASTA format)
Description	Melanocortin receptor 4 (MC4-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Brain, placental, and gut tissues.
Post translational modification	N/A
Function	Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase.
Protein Length	332 Amino acids
Molecular weight	36943
Domain Name	7tm_1
References	1  PubMed abstract 8392067 2  PubMed abstract 7854347 3   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15489334 5  PubMed abstract 10199800 6  PubMed abstract 11443223 7  PubMed abstract 8392067 8  PubMed abstract 7854347 9   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 10  PubMed abstract 15489334 11  PubMed abstract 10199800 12  PubMed abstract 11443223
Hormone	N/A
Gene ID	4160
PDB ID	2IQP   2IQR   2IQS   2IQU   2IQV   2IQW
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 52

HMRbase accession number	20436
Swiss-prot Accession number	P33032 (Sequence in FASTA format)
Description	Melanocortin receptor 5 (MC5-R) (MC-2).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed in the brain but not in the melanoma cells.
Post translational modification	N/A
Function	Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
Protein Length	325 Amino acids
Molecular weight	36601
Domain Name	7tm_1
References	1  PubMed abstract 8396929 2  PubMed abstract 8179577 3  PubMed abstract 7739752 4   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 15489334 6  PubMed abstract 9240466 7  PubMed abstract 11286624
Hormone	N/A
Gene ID	4161
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 53

HMRbase accession number	20459
Swiss-prot Accession number	Q502V1 (Sequence in FASTA format)
Description	Melanocortin 5 receptor.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	325 Amino acids
Molecular weight	36567
Domain Name	7tm_1
References	1  PubMed abstract 12477932 2   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 54

HMRbase accession number	20469
Swiss-prot Accession number	Q66K38 (Sequence in FASTA format)
Description	Melanocortin 1 receptor (Alpha melanocyte stimulating hormonereceptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34652
Domain Name	7tm_1
References	1  PubMed abstract 12477932 2   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases. 3   Nakayama K., Soemantri A., Jin F., Dashnyam B., Ohtsuka R.,Duanchang P., Isa M.N., Ishida W.S., Harihara S., Ishida T.; "Identification of novel functional variants of the melanocortin 1receptor gene originated from Asians."; Hum. Genet. 0:0-0(2006).
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 55

HMRbase accession number	20518
Swiss-prot Accession number	Q6UR92 (Sequence in FASTA format)
Description	Melanocortin 1 receptor variant V265I.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34720
Domain Name	7tm_1
References	1   Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 56

HMRbase accession number	20519
Swiss-prot Accession number	Q6UR93 (Sequence in FASTA format)
Description	Melanocortin 1 receptor variant A222T.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34736
Domain Name	7tm_1
References	1   Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 57

HMRbase accession number	20520
Swiss-prot Accession number	Q6UR94 (Sequence in FASTA format)
Description	Melanocortin 1 receptor variant A111V.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34734
Domain Name	7tm_1
References	1   Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 58

HMRbase accession number	20521
Swiss-prot Accession number	Q6UR95 (Sequence in FASTA format)
Description	Melanocortin 1 receptor variant C315R.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34759
Domain Name	7tm_1
References	1   Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 59

HMRbase accession number	20522
Swiss-prot Accession number	Q6UR96 (Sequence in FASTA format)
Description	Melanocortin 1 receptor variant T308M.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34736
Domain Name	7tm_1
References	1   Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 60

HMRbase accession number	20523
Swiss-prot Accession number	Q6UR97 (Sequence in FASTA format)
Description	Melanocortin 1 receptor variant R213W.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34736
Domain Name	7tm_1
References	1   Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 61

HMRbase accession number	20524
Swiss-prot Accession number	Q6UR98 (Sequence in FASTA format)
Description	Melanocortin 1 receptor variant R160Q.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34677
Domain Name	7tm_1
References	1   Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 62

HMRbase accession number	20525
Swiss-prot Accession number	Q6UR99 (Sequence in FASTA format)
Description	Melanocortin 1 receptor variant S83L.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34732
Domain Name	7tm_1
References	1   Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 63

HMRbase accession number	20526
Swiss-prot Accession number	Q6URA0 (Sequence in FASTA format)
Description	Melanocortin 1 receptor variant F45L.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34671
Domain Name	7tm_1
References	1   Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 64

HMRbase accession number	20566
Swiss-prot Accession number	Q86YW1 (Sequence in FASTA format)
Description	Melanocortin 1 receptor variant L93R.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34749
Domain Name	7tm_1
References	1  PubMed abstract 12473109 2   Sanchez Mas J.M., Olivares C., Lozano J.A., Garcia-Borron J.C.,Jimenez-Cervantes C.; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 65

HMRbase accession number	20592
Swiss-prot Accession number	Q541E0 (Sequence in FASTA format)
Description	Somatostatin receptor subtype 5.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	364 Amino acids
Molecular weight	39202
Domain Name	7tm_1
References	1  PubMed abstract 12072395
Hormone	N/A
Gene ID	6755
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 66

HMRbase accession number	20599
Swiss-prot Accession number	O15218 (Sequence in FASTA format)
Description	Adrenomedullin receptor (AM-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver.
Post translational modification	N/A
Function	Receptor for adrenomedullin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity).
Protein Length	404 Amino acids
Molecular weight	45323
Domain Name	7tm_1
References	1  PubMed abstract 9367907 2   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 15489334
Hormone	N/A
Gene ID	11318
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 67

HMRbase accession number	20643
Swiss-prot Accession number	O43193 (Sequence in FASTA format)
Description	Motilin receptor (G-protein coupled receptor 38).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed only in thyroid, stomach, and bone marrow.
Post translational modification	N/A
Function	Receptor for motilin.
Protein Length	412 Amino acids
Molecular weight	45344
Domain Name	7tm_1
References	1  PubMed abstract 9441746 2  PubMed abstract 10381885 3   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15057823 5  PubMed abstract 11322507
Hormone	N/A
Gene ID	2862
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 68

HMRbase accession number	20649
Swiss-prot Accession number	Q6ISR8 (Sequence in FASTA format)
Description	Growth hormone secretagogue receptor.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	289 Amino acids
Molecular weight	32153
Domain Name	7tm_1
References	1  PubMed abstract 12477932 2   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	2693
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 69

HMRbase accession number	20658
Swiss-prot Accession number	P48039 (Sequence in FASTA format)
Description	Melatonin receptor type 1A (Mel-1A-R) (Mel1a melatonin receptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus.
Post translational modification	N/A
Function	High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Protein Length	350 Amino acids
Molecular weight	39375
Domain Name	7tm_1
References	1  PubMed abstract 7946354 2  PubMed abstract 10471411 3  PubMed abstract 15489334
Hormone	Detail in HMRbase
Gene ID	4543
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 70

HMRbase accession number	20662
Swiss-prot Accession number	P49286 (Sequence in FASTA format)
Description	Melatonin receptor type 1B (Mel-1B-R) (Mel1b melatonin receptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed in retina and less in brain and hippocampus.
Post translational modification	N/A
Function	High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Protein Length	362 Amino acids
Molecular weight	40188
Domain Name	7tm_1
References	1  PubMed abstract 7568007 2  PubMed abstract 10696804 3   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15489334
Hormone	N/A
Gene ID	4544
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 71

HMRbase accession number	20666
Swiss-prot Accession number	Q13585 (Sequence in FASTA format)
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Hypothalamus and pituitary.
Post translational modification	N/A
Function	Does not bind melatonin.
Protein Length	613 Amino acids
Molecular weight	66924
Domain Name	7tm_1
References	1  PubMed abstract 8647286
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 72

HMRbase accession number	20677
Swiss-prot Accession number	Q16602 (Sequence in FASTA format)
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1receptor) (Calcitonin receptor-like receptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	Predominantly expressed in the lung and heart.
Post translational modification	N/A
Function	Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Protein Length	461 Amino acids
Molecular weight	52979
Domain Name	7tm_2  HRM
References	1  PubMed abstract 8626685 2  PubMed abstract 7818539 3   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15340161
Hormone	N/A
Gene ID	10203
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 73

HMRbase accession number	20697
Swiss-prot Accession number	Q4QRJ1 (Sequence in FASTA format)
Description	Corticotropin releasing hormone receptor 1.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	415 Amino acids
Molecular weight	47671
Domain Name	7tm_2  HRM
References	1  PubMed abstract 12477932 2   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	1394
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 74

HMRbase accession number	20713
Swiss-prot Accession number	P43220 (Sequence in FASTA format)
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R)(GLP-1R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Protein Length	463 Amino acids
Molecular weight	53060
Domain Name	7tm_2  HRM
References	1  PubMed abstract 8405712 2  PubMed abstract 8404634 3  PubMed abstract 8216285 4  PubMed abstract 7517895 5  PubMed abstract 7843404 6   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 7   Rieder M.J., Livingston R.J., Daniels M.R., Montoya M.A., Chung M.-W.,Miyamoto K.E., Nguyen C.P., Nguyen D.A., Poel C.L., Robertson P.D.,Schackwitz W.S., Sherwood J.K., Witrak L.A., Nickerson D.A.; "NIEHS-SNPs, environmental genome project, NIEHS ES15478, Departmentof Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 8  PubMed abstract 14574404 9  PubMed abstract 15489334 10  PubMed abstract 9213353 11  PubMed abstract 8405712 12  PubMed abstract 8404634 13  PubMed abstract 8216285 14  PubMed abstract 7517895 15  PubMed abstract 7843404 16   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 17   Rieder M.J., Livingston R.J., Daniels M.R., Montoya M.A., Chung M.-W.,Miyamoto K.E., Nguyen C.P., Nguyen D.A., Poel C.L., Robertson P.D.,Schackwitz W.S., Sherwood J.K., Witrak L.A., Nickerson D.A.; "NIEHS-SNPs, environmental genome project, NIEHS ES15478, Departmentof Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 18  PubMed abstract 14574404 19  PubMed abstract 15489334 20  PubMed abstract 9213353
Hormone	N/A
Gene ID	2740
PDB ID	3C59   3C5T
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 75

HMRbase accession number	20716
Swiss-prot Accession number	O95838 (Sequence in FASTA format)
Description	Glucagon-like peptide 2 receptor precursor (GLP-2 receptor) (GLP-2-R)(GLP-2R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Protein Length	553 Amino acids
Molecular weight	63001
Domain Name	7tm_2  HRM
References	1  PubMed abstract 9990065
Hormone	N/A
Gene ID	9340
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 76

HMRbase accession number	20718
Swiss-prot Accession number	Q4VAT3 (Sequence in FASTA format)
Description	Glucagon-like peptide 2 receptor.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	553 Amino acids
Molecular weight	63000
Domain Name	7tm_2  HRM
References	1  PubMed abstract 12477932 2   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 77

HMRbase accession number	20729
Swiss-prot Accession number	Q9HB45 (Sequence in FASTA format)
Description	GHRH receptor splice variant 1.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	359 Amino acids
Molecular weight	40167
Domain Name	7tm_2
References	1  PubMed abstract 10962031
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 78

HMRbase accession number	20742
Swiss-prot Accession number	Q53T00 (Sequence in FASTA format)
Description	Hypothetical protein SCTR.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	440 Amino acids
Molecular weight	50207
Domain Name	7tm_2  HRM
References	1   Sun H., Haakenson W., Conners J.; "The sequence of Homo sapiens BAC clone RP11-464C8."; Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases. 2   Waterston R.H.; Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases. 3   Waterston R.; Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases. 4   Wilson R.K.; Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	6344
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 79

HMRbase accession number	20746
Swiss-prot Accession number	P35348 (Sequence in FASTA format)
Description	Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A-adrenoreceptor) (Alpha-1C adrenergic receptor) (Alpha adrenergicreceptor 1c).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart.
Post translational modification	Carboxyl-terminal Ser or Thr residues may be phosphorylated (By similarity).
Function	This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins.
Protein Length	466 Amino acids
Molecular weight	51487
Domain Name	7tm_1
References	1  PubMed abstract 8396931 2  PubMed abstract 8024574 3  PubMed abstract 8183249 4  PubMed abstract 8564208 5  PubMed abstract 7815325 6  PubMed abstract 7737411 7  PubMed abstract 9490024 8  PubMed abstract 10493934 9   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 10   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 11  PubMed abstract 8832064 12  PubMed abstract 15179408
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	148
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 80

HMRbase accession number	20751
Swiss-prot Accession number	P35368 (Sequence in FASTA format)
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B-adrenoreceptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Protein Length	520 Amino acids
Molecular weight	56836
Domain Name	7tm_1
References	1  PubMed abstract 1328250 2  PubMed abstract 8183249 3  PubMed abstract 7815325
Hormone	Detail in HMRbase
Gene ID	147
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 81

HMRbase accession number	20755
Swiss-prot Accession number	P25100 (Sequence in FASTA format)
Description	Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D-adrenoreceptor) (Alpha-1A adrenergic receptor) (Alpha adrenergicreceptor 1a).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.
Protein Length	572 Amino acids
Molecular weight	60463
Domain Name	7tm_1
References	1  PubMed abstract 1656955 2  PubMed abstract 8183249 3  PubMed abstract 7815325 4  PubMed abstract 8024574 5  PubMed abstract 7746284 6  PubMed abstract 11780052
Hormone	Detail in HMRbase
Gene ID	146
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 82

HMRbase accession number	20761
Swiss-prot Accession number	P08913 (Sequence in FASTA format)
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha-2AAR) (Alpha-2 adrenergic receptor subtypeC10).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.
Protein Length	450 Amino acids
Molecular weight	48957
Domain Name	7tm_1
References	1  PubMed abstract 2568356 2  PubMed abstract 2823383 3  PubMed abstract 2170371 4  PubMed abstract 10948191 5  PubMed abstract 16567612 6   Mao Z.-M., Tang K., Li B.-M., Jing N.-H.; "Cloning and expression of human alpha-2A adrenergic receptor in SY5Ycells."; Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. 7   Castellano M., Giacche' M., Rossi F., Rivadossi F., Perani C.,Beschi M., Agabiti Rosei E.; "A search for genetic variability in the human alpha-2 adrenergicreceptor on chromosome 10."; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. 8   Liu L., Yuan L.; "Human alpha-2A adrenergic receptor gene and the genotype of -1296nucleotide and motionsickness."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases. 9   Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. 10  PubMed abstract 15164054 11  PubMed abstract 15489334 12  PubMed abstract 1849485 13  PubMed abstract 1678390 14  PubMed abstract 1678850 15  PubMed abstract 17081983 16  PubMed abstract 11888275 17  PubMed abstract 2568356 18  PubMed abstract 2823383 19  PubMed abstract 2170371 20  PubMed abstract 10948191 21  PubMed abstract 16567612 22   Mao Z.-M., Tang K., Li B.-M., Jing N.-H.; "Cloning and expression of human alpha-2A adrenergic receptor in SY5Ycells."; Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. 23   Castellano M., Giacche' M., Rossi F., Rivadossi F., Perani C.,Beschi M., Agabiti Rosei E.; "A search for genetic variability in the human alpha-2 adrenergicreceptor on chromosome 10."; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. 24   Liu L., Yuan L.; "Human alpha-2A adrenergic receptor gene and the genotype of -1296nucleotide and motionsickness."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases. 25   Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. 26  PubMed abstract 15164054 27  PubMed abstract 15489334 28  PubMed abstract 1849485 29  PubMed abstract 1678390 30  PubMed abstract 1678850 31  PubMed abstract 17081983 32  PubMed abstract 11888275
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	150
PDB ID	1HLL   1HO9   1HOD   1HOF
Drugpedia	wiki
Comments

Search Result - 83

HMRbase accession number	20766
Swiss-prot Accession number	P18089 (Sequence in FASTA format)
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor) (Alpha-2 adrenergic receptor subtype C2).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
Protein Length	450 Amino acids
Molecular weight	49954
Domain Name	7tm_1
References	1  PubMed abstract 2164221 2  PubMed abstract 2172775 3  PubMed abstract 11056163 4  PubMed abstract 15037199 5   Kopatz S.A., Aronstam R.S., Sharma S.V.; "Isolation of complete coding sequence for adrenergic receptor alpha2B (ADRA2B)."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. 6   Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 15815621 8  PubMed abstract 2173582
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	151
PDB ID	2CVA
Drugpedia	wiki
Comments

Search Result - 84

HMRbase accession number	20771
Swiss-prot Accession number	P18825 (Sequence in FASTA format)
Description	Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2Cadrenoreceptor) (Alpha-2 adrenergic receptor subtype C4).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins.
Protein Length	462 Amino acids
Molecular weight	49522
Domain Name	7tm_1
References	1  PubMed abstract 2842764 2  PubMed abstract 9371698 3   Yano K., Takeda M., Sugimoto E., Sagai H.; "Molecular cloning and expression of a novel human alpha2C-adrenergincreceptor, alpha2CII, gene."; Submitted (OCT-1992) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 10801795 5  PubMed abstract 15319474 6   Kopatz S.A., Aronstam R.S., Sharma S.V.; "Isolation of complete coding sequence for adrenergic receptor alpha2C (ADRA2C)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 1849485
Hormone	Detail in HMRbase
Gene ID	152
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 85

HMRbase accession number	20780
Swiss-prot Accession number	P08588 (Sequence in FASTA format)
Description	Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein. Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
Protein Length	477 Amino acids
Molecular weight	51323
Domain Name	7tm_1
References	1  PubMed abstract 2825170 2  PubMed abstract 10477438 3   Rieder M.J., Daniels R.L., da Ponte S.H., Hastings N.C., Ahearn M.O.,Rajkumar N., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15358775 5  PubMed abstract 10212248 6  PubMed abstract 11052857 7  PubMed abstract 11854867
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 86

HMRbase accession number	20790
Swiss-prot Accession number	P07550 (Sequence in FASTA format)
Description	Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation. Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK.
Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Protein Length	413 Amino acids
Molecular weight	46557
Domain Name	7tm_1
References	1  PubMed abstract 3033609 2  PubMed abstract 3025863 3  PubMed abstract 3026848 4  PubMed abstract 2823249 5  PubMed abstract 3034889 6   Rupert J.R., Hochachka P.W.; "Beta-2-adrenergic receptor allele frequencies in two native Americanpopulations."; Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases. 7   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. 8   Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. 9  PubMed abstract 2831218 10  PubMed abstract 2540197 11  PubMed abstract 11146000 12  PubMed abstract 10499588 13  PubMed abstract 12142540 14  PubMed abstract 8383511 15  PubMed abstract 7915137 16  PubMed abstract 7706471
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	154
PDB ID	2R4R   2R4S   3D4S
Drugpedia	wiki
Comments

Search Result - 87

HMRbase accession number	20801
Swiss-prot Accession number	P13945 (Sequence in FASTA format)
Description	Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed mainly in adipose tissues.
Post translational modification	N/A
Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Protein Length	408 Amino acids
Molecular weight	43519
Domain Name	7tm_1
References	1  PubMed abstract 2570461 2  PubMed abstract 8389293 3  PubMed abstract 8389717 4   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases. 5   Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 15489334 7  PubMed abstract 1336117 8  PubMed abstract 7609752 9  PubMed abstract 8721782 10  PubMed abstract 8641219 11  PubMed abstract 10391210
Hormone	Detail in HMRbase
Gene ID	155
PDB ID	2CDW
Drugpedia	wiki
Comments

Search Result - 88

HMRbase accession number	20814
Swiss-prot Accession number	Q4VBM7 (Sequence in FASTA format)
Description	Adrenergic, alpha-1A-, receptor.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity).
Protein Length	466 Amino acids
Molecular weight	51512
Domain Name	7tm_1
References	1  PubMed abstract 12477932 2   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 89

HMRbase accession number	20815
Swiss-prot Accession number	Q5T5Y4 (Sequence in FASTA format)
Description	Adrenergic, beta-1-, receptor.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity (By similarity).
Protein Length	477 Amino acids
Molecular weight	51224
Domain Name	7tm_1
References	1   Heath P.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	153
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 90

HMRbase accession number	20817
Swiss-prot Accession number	Q6GMT4 (Sequence in FASTA format)
Description	Adrenergic, beta-2-, receptor, surface.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity).
Protein Length	413 Amino acids
Molecular weight	46459
Domain Name	7tm_1
References	1  PubMed abstract 12477932 2   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 91

HMRbase accession number	20839
Swiss-prot Accession number	Q96RE8 (Sequence in FASTA format)
Description	Adrenergic receptor alpha-1a.
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity).
Protein Length	466 Amino acids
Molecular weight	51431
Domain Name	7tm_1
References	1   Banerjee A.G.N., Aarti A.; "RT-PCR cloning and sequence analysis of adrenergic receptor subtype-alpha-1a cDNA from human prostrate cell-line DU-145."; Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 92

HMRbase accession number	20856
Swiss-prot Accession number	P37288 (Sequence in FASTA format)
Description	Vasopressin V1a receptor (V1aR) (Vascular/hepatic-type argininevasopressin receptor) (Antidiuretic hormone receptor 1a) (AVPR V1a).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.
Protein Length	418 Amino acids
Molecular weight	46800
Domain Name	7tm_1  DUF1856
References	1  PubMed abstract 8106369 2  PubMed abstract 8074728 3  PubMed abstract 9357056 4  PubMed abstract 9581826 5   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 15489334 7  PubMed abstract 12082568 8  PubMed abstract 16511036 9  PubMed abstract 8106369 10  PubMed abstract 8074728 11  PubMed abstract 9357056 12  PubMed abstract 9581826 13   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 14  PubMed abstract 15489334 15  PubMed abstract 12082568 16  PubMed abstract 16511036
Hormone	N/A
Gene ID	552
PDB ID	1YTV
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 93

HMRbase accession number	20862
Swiss-prot Accession number	P47901 (Sequence in FASTA format)
Description	Vasopressin V1b receptor (V1bR) (AVPR V1b) (Vasopressin V3 receptor)(AVPR V3) (Antidiuretic hormone receptor 1b).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system.
Protein Length	424 Amino acids
Molecular weight	46971
Domain Name	7tm_1
References	1  PubMed abstract 7929452 2  PubMed abstract 7805841 3  PubMed abstract 9357056 4  PubMed abstract 9581826 5  PubMed abstract 10607899 6   Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 16710414 8  PubMed abstract 7929452 9  PubMed abstract 7805841 10  PubMed abstract 9357056 11  PubMed abstract 9581826 12  PubMed abstract 10607899 13   Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. 14  PubMed abstract 16710414
Hormone	N/A
Gene ID	553
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 94

HMRbase accession number	20867
Swiss-prot Accession number	P30518 (Sequence in FASTA format)
Description	Vasopressin V2 receptor (Renal-type arginine vasopressin receptor)(Antidiuretic hormone receptor) (AVPR V2).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Kidney.
Post translational modification	N/A
Function	Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Protein Length	371 Amino acids
Molecular weight	40279
Domain Name	7tm_1
References	1  PubMed abstract 1534149 2  PubMed abstract 1415251 3  PubMed abstract 8735975 4  PubMed abstract 9581826 5   Warren C.N., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 15489334 7  PubMed abstract 9224808 8  PubMed abstract 1356229 9  PubMed abstract 1303271 10  PubMed abstract 1303257 11  PubMed abstract 8267567 12  PubMed abstract 8479490 13  PubMed abstract 8514744 14  PubMed abstract 8037205 15  PubMed abstract 7999078 16  PubMed abstract 7987330 17  PubMed abstract 7833930 18  PubMed abstract 8045948 19  PubMed abstract 7984150 20  PubMed abstract 8078903 21  PubMed abstract 7560098 22  PubMed abstract 9402087 23  PubMed abstract 9452109 24  PubMed abstract 10694923 25  PubMed abstract 9711877 26  PubMed abstract 10770218 27  PubMed abstract 11026555 28  PubMed abstract 11232028 29  PubMed abstract 11916004 30  PubMed abstract 15872203 31  PubMed abstract 1534149 32  PubMed abstract 1415251 33  PubMed abstract 8735975 34  PubMed abstract 9581826 35   Warren C.N., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 36  PubMed abstract 15489334 37  PubMed abstract 9224808 38  PubMed abstract 1356229 39  PubMed abstract 1303271 40  PubMed abstract 1303257 41  PubMed abstract 8267567 42  PubMed abstract 8479490 43  PubMed abstract 8514744 44  PubMed abstract 8037205 45  PubMed abstract 7999078 46  PubMed abstract 7987330 47  PubMed abstract 7833930 48  PubMed abstract 8045948 49  PubMed abstract 7984150 50  PubMed abstract 8078903 51  PubMed abstract 7560098 52  PubMed abstract 9402087 53  PubMed abstract 9452109 54  PubMed abstract 10694923 55  PubMed abstract 9711877 56  PubMed abstract 10770218 57  PubMed abstract 11026555 58  PubMed abstract 11232028 59  PubMed abstract 11916004 60  PubMed abstract 15872203 61  PubMed abstract 1534149 62  PubMed abstract 1415251 63  PubMed abstract 8735975 64  PubMed abstract 9581826 65   Warren C.N., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 66  PubMed abstract 15489334 67  PubMed abstract 9224808 68  PubMed abstract 1356229 69  PubMed abstract 1303271 70  PubMed abstract 1303257 71  PubMed abstract 8267567 72  PubMed abstract 8479490 73  PubMed abstract 8514744 74  PubMed abstract 8037205 75  PubMed abstract 7999078 76  PubMed abstract 7987330 77  PubMed abstract 7833930 78  PubMed abstract 8045948 79  PubMed abstract 7984150 80  PubMed abstract 8078903 81  PubMed abstract 7560098 82  PubMed abstract 9402087 83  PubMed abstract 9452109 84  PubMed abstract 10694923 85  PubMed abstract 9711877 86  PubMed abstract 10770218 87  PubMed abstract 11026555 88  PubMed abstract 11232028 89  PubMed abstract 11916004 90  PubMed abstract 15872203
Hormone	N/A
Gene ID	554
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 95

HMRbase accession number	20979
Swiss-prot Accession number	P06213 (Sequence in FASTA format)
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen)[Contains: Insulin receptor subunit alpha; Insulin receptor subunitbeta].
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; Single-pass type I membrane protein
Developmental Stage	N/A
Similarity	Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain.
Tissue Specificity	Isoform Long and isoform Short are expressed in the peripheral nerve, kidney, liver, striated muscle, fibroblasts and skin. Isoform Short is expressed also in the spleen and lymphoblasts.
Post translational modification	After being transported from the endoplasmic reticulum to the Golgi apparatus, the single glycosylated precursor is further glycosylated and then cleaved, followed by its transport to the plasma membrane. Autophosphorylated on tyrosine residues in response to insulin. Phosphorylation of Tyr-999 is required for IRS1- and SHC1- binding.
Function	This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. Mediates the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1.
Protein Length	1382 Amino acids
Molecular weight	156307
Domain Name	Pkinase_Tyr  Recep_L_domain  Furin-like  Pkinase
References	1  PubMed abstract 2859121 2  PubMed abstract 2983222 3   Chen E.Y.; Submitted (JUL-1985) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 2210055 5  PubMed abstract 3447155 6  PubMed abstract 2211730 7  PubMed abstract 3680248 8  PubMed abstract 2777789 9  PubMed abstract 2806055 10  PubMed abstract 2280779 11  PubMed abstract 2538124 12  PubMed abstract 2369896 13  PubMed abstract 2566545 14  PubMed abstract 3166375 15  PubMed abstract 2544997 16  PubMed abstract 1472036 17  PubMed abstract 1321605 18  PubMed abstract 2842060 19  PubMed abstract 3101064 20  PubMed abstract 8276809 21  PubMed abstract 7559478 22  PubMed abstract 7537849 23  PubMed abstract 11374898 24  PubMed abstract 16127460 25  PubMed abstract 15951569 26  PubMed abstract 7997262 27  PubMed abstract 9312016 28  PubMed abstract 14690593 29  PubMed abstract 3283938 30  PubMed abstract 2834824 31  PubMed abstract 2479553 32  PubMed abstract 2544998 33  PubMed abstract 2168397 34  PubMed abstract 2121734 35  PubMed abstract 2365819 36  PubMed abstract 1963473 37  PubMed abstract 2040394 38  PubMed abstract 2002058 39  PubMed abstract 1890161 40  PubMed abstract 1607067 41  PubMed abstract 1607076 42  PubMed abstract 1563582 43  PubMed abstract 1730625 44  PubMed abstract 1470163 45  PubMed abstract 8432414 46  PubMed abstract 8243830 47  PubMed abstract 8458533 48  PubMed abstract 8390949 49  PubMed abstract 8242067 50  PubMed abstract 8096518 51  PubMed abstract 8388389 52  PubMed abstract 8326490 53  PubMed abstract 8419945 54  PubMed abstract 8288049 55  PubMed abstract 8314008 56  PubMed abstract 8082780 57  PubMed abstract 8188715 58  PubMed abstract 7983039 59  PubMed abstract 7815442 60  PubMed abstract 7657032 61  PubMed abstract 7538143 62  PubMed abstract 8890729 63  PubMed abstract 8636294 64  PubMed abstract 9199575 65  PubMed abstract 9175790 66  PubMed abstract 9299395 67  PubMed abstract 9249867 68   ; Desbois-Mouthon C., Girodon E., Ghanem N., Caron M., Pennerath A.,Conteville P., Magre J., Besmond C., Goossens M., Capeau J.,Amselem S.; "Molecular analysis of the insulin receptor gene for prenataldiagnosis of leprechaunism in two families."; Prenat. Diagn. 17:657-663(1997). 69  PubMed abstract 9703342 70  PubMed abstract 10443650 71  PubMed abstract 10733238 72  PubMed abstract 11260230 73  PubMed abstract 12107746 74  PubMed abstract 12023989 75  PubMed abstract 12538626 76  PubMed abstract 12970295 77  PubMed abstract 15161766 78  PubMed abstract 17201797
Hormone	P01308   Detail in HMRbase
Gene ID	N/A
PDB ID	1GAG   1I44   1IR3   1IRK   1P14   1RQQ   2AUH   2B4S   2DTG   2HR7   2Z8C   3BU3   3BU5   3BU6
Drugpedia	wiki
Comments

Search Result - 96

HMRbase accession number	20980
Swiss-prot Accession number	P10912 (Sequence in FASTA format)
Description	Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)].
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; single-pass type I membrane protein. GHBP: Secreted protein. Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity). Isoform 2 remains fixed to the cell membrane and is not internalized. The proteolytic processed protein, GHBP, is secreted
Developmental Stage	N/A
Similarity	Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain.
Tissue Specificity	Expressed in various tissues with high expression in liver and skeletal muscle. Isoform 4 is predominantly expressed in kidney, bladder, adrenal gland and brain stem. In the placenta, isoform 1 predominantly expressed in chorion and decidua, isoform 4 highly expressed in villi. Isoform 2 is expressed in lung, stomach and muscle. Low levels in liver.
Post translational modification	The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. Shedding is inhibited by growth hormone (GH) binding to the receptor probably due to a conformational change in GHR rendering the receptor inaccessible to ADAM17 (By similarity). On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity).
Function	Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
Protein Length	638 Amino acids
Molecular weight	71500
Domain Name	N/A
References	1  PubMed abstract 2825030 2  PubMed abstract 2813379 3  PubMed abstract 1569971 4  PubMed abstract 8855247 5  PubMed abstract 9360546 6  PubMed abstract 9058373 7   Orlovsky I.V., Borovikova I.E., Rubtsov P.M.; "Comparing of nucleotide sequences of alternatively spliced region ofmammalian growth hormone receptor genes."; Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. 8  PubMed abstract 8360189 9  PubMed abstract 10764769 10  PubMed abstract 2406245 11  PubMed abstract 11785980 12  PubMed abstract 2779634 13  PubMed abstract 8421103 14  PubMed abstract 8504296 15  PubMed abstract 8137822 16  PubMed abstract 7565946 17  PubMed abstract 9024232 18  PubMed abstract 9814495 19  PubMed abstract 9851797 20  PubMed abstract 10391209 21   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 22  PubMed abstract 10870033 23  PubMed abstract 14678285 24  PubMed abstract 1549776 25  PubMed abstract 8943276
Hormone	P01241   Detail in HMRbase
Gene ID	2690
PDB ID	1A22   1AXI   1HWG   1HWH   1KF9   2AEW   3HHR
Drugpedia	wiki
Comments

Search Result - 97

HMRbase accession number	20986
Swiss-prot Accession number	P16471 (Sequence in FASTA format)
Description	Prolactin receptor precursor (PRL-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; Single-pass type I membrane protein. Secreted. Note=Isoform 7
Developmental Stage	N/A
Similarity	Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 2 fibronectin type-III domains.
Tissue Specificity	Expressed in breast, placenta, kidney, liver and pancreas.
Post translational modification	N/A
Function	This is a receptor for the anterior pituitary hormone prolactin. Isoforms 4 and 6 are unable to transduce prolactin signaling.
Protein Length	622 Amino acids
Molecular weight	69506
Domain Name	fn3
References	1  PubMed abstract 2558309 2  PubMed abstract 10585417 3  PubMed abstract 10084611 4  PubMed abstract 11518703 5  PubMed abstract 12351696 6  PubMed abstract 12580759 7  PubMed abstract 15489334 8  PubMed abstract 7768908 9  PubMed abstract 16740656 10  PubMed abstract 7984244
Hormone	P01236   Detail in HMRbase
Gene ID	5618
PDB ID	1BP3   3D48
Drugpedia	wiki
Comments

Search Result - 98

HMRbase accession number	20987
Swiss-prot Accession number	P16473 (Sequence in FASTA format)
Description	Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormonereceptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 6 LRR (leucine-rich) repeats.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
Protein Length	764 Amino acids
Molecular weight	86830
Domain Name	7tm_1  LRR_1
References	1  PubMed abstract 2558651 2  PubMed abstract 2610690 3  PubMed abstract 2302212 4  PubMed abstract 2293030 5   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 1530609 7  PubMed abstract 11502179 8  PubMed abstract 12045258 9  PubMed abstract 8747461 10  PubMed abstract 11887032 11  PubMed abstract 12593721 12  PubMed abstract 12930595 13  PubMed abstract 10870027 14  PubMed abstract 1955520 15  PubMed abstract 8413627 16  PubMed abstract 7508946 17  PubMed abstract 8045989 18  PubMed abstract 7989485 19  PubMed abstract 7920658 20  PubMed abstract 7556878 21  PubMed abstract 7800007 22  PubMed abstract 7528344 23  PubMed abstract 7647578 24  PubMed abstract 7488864 25  PubMed abstract 8636266 26  PubMed abstract 8964822 27  PubMed abstract 8954020 28  PubMed abstract 9062474 29  PubMed abstract 9100579 30  PubMed abstract 9253356 31  PubMed abstract 9329388 32  PubMed abstract 9360555 33  PubMed abstract 9398746 34  PubMed abstract 9185526 35  PubMed abstract 9294132 36  PubMed abstract 9349581 37  PubMed abstract 9589634 38  PubMed abstract 9854118 39  PubMed abstract 10199795 40  PubMed abstract 10487707 41  PubMed abstract 10037070 42  PubMed abstract 10560955 43  PubMed abstract 11022192 44  PubMed abstract 10651846 45  PubMed abstract 10720030 46  PubMed abstract 10852462 47  PubMed abstract 10946859 48  PubMed abstract 11095460 49  PubMed abstract 11127522 50  PubMed abstract 11081252 51  PubMed abstract 11128715 52  PubMed abstract 11201847 53  PubMed abstract 11517004 54  PubMed abstract 11549687 55  PubMed abstract 11434721 56  PubMed abstract 11442002 57  PubMed abstract 12213664 58  PubMed abstract 12050212 59  PubMed abstract 12589819 60  PubMed abstract 12788902 61  PubMed abstract 14759073 62  PubMed abstract 14725684 63  PubMed abstract 15163335 64  PubMed abstract 15531543
Hormone	P01215   Detail in HMRbase    P01222   Detail in HMRbase    Q86YW7   Detail in HMRbase    Q96T91   Detail in HMRbase
Gene ID	N/A
PDB ID	1XUM
Drugpedia	wiki
Comments

Search Result - 99

HMRbase accession number	20996
Swiss-prot Accession number	P22888 (Sequence in FASTA format)
Description	Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH-R) (Luteinizing hormone receptor) (LHR).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 7 LRR (leucine-rich) repeats.
Tissue Specificity	Gonadal and thyroid cells.
Post translational modification	N/A
Function	Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Protein Length	699 Amino acids
Molecular weight	78616
Domain Name	7tm_1  LRR_1
References	1  PubMed abstract 2244890 2  PubMed abstract 1922095 3  PubMed abstract 2293030 4  PubMed abstract 7556872 5  PubMed abstract 9858858 6  PubMed abstract 8747461 7  PubMed abstract 15539429 8  PubMed abstract 7692306 9  PubMed abstract 8281137 10  PubMed abstract 7757065 11  PubMed abstract 7714085 12  PubMed abstract 7629248 13  PubMed abstract 7719343 14  PubMed abstract 8829636 15  PubMed abstract 8929952 16  PubMed abstract 8559204 17  PubMed abstract 9215288 18  PubMed abstract 10215412 19  PubMed abstract 9467560 20  PubMed abstract 9626144 21  PubMed abstract 9661624 22  PubMed abstract 9851790 23  PubMed abstract 9514160 24  PubMed abstract 9626653 25  PubMed abstract 10580072
Hormone	P01215   Detail in HMRbase    P01229   Detail in HMRbase
Gene ID	3973
PDB ID	1LUT   1XUL
Drugpedia	wiki
Comments

Search Result - 100

HMRbase accession number	20998
Swiss-prot Accession number	P23945 (Sequence in FASTA format)
Description	Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats.
Tissue Specificity	Sertoli cells and ovarian granulosa cells.
Post translational modification	N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity).
Function	Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Protein Length	695 Amino acids
Molecular weight	78295
Domain Name	N/A
References	1  PubMed abstract 1709010 2  PubMed abstract 1301382 3  PubMed abstract 1322283 4   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 15489334 6  PubMed abstract 1359889 7  PubMed abstract 7926278 8  PubMed abstract 7916967 9  PubMed abstract 8747461 10  PubMed abstract 15662415 11  PubMed abstract 7553856 12  PubMed abstract 9100567 13  PubMed abstract 9851774 14  PubMed abstract 9769327 15  PubMed abstract 10391209 16   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 17  PubMed abstract 12059813 18  PubMed abstract 11889179 19  PubMed abstract 12930927 20  PubMed abstract 12930928 21  PubMed abstract 1709010 22  PubMed abstract 1301382 23  PubMed abstract 1322283 24   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 25  PubMed abstract 15489334 26  PubMed abstract 1359889 27  PubMed abstract 7926278 28  PubMed abstract 7916967 29  PubMed abstract 8747461 30  PubMed abstract 15662415 31  PubMed abstract 7553856 32  PubMed abstract 9100567 33  PubMed abstract 9851774 34  PubMed abstract 9769327 35  PubMed abstract 10391209 36   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 37  PubMed abstract 12059813 38  PubMed abstract 11889179 39  PubMed abstract 12930927 40  PubMed abstract 12930928 41  PubMed abstract 1709010 42  PubMed abstract 1301382 43  PubMed abstract 1322283 44   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 45  PubMed abstract 15489334 46  PubMed abstract 1359889 47  PubMed abstract 7926278 48  PubMed abstract 7916967 49  PubMed abstract 8747461 50  PubMed abstract 15662415 51  PubMed abstract 7553856 52  PubMed abstract 9100567 53  PubMed abstract 9851774 54  PubMed abstract 9769327 55  PubMed abstract 10391209 56   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 57  PubMed abstract 12059813 58  PubMed abstract 11889179 59  PubMed abstract 12930927 60  PubMed abstract 12930928
Hormone	P01215   Detail in HMRbase    P01225   Detail in HMRbase
Gene ID	2492
PDB ID	1XUN   1XWD
Drugpedia	wiki
Comments

Search Result - 101

HMRbase accession number	21003
Swiss-prot Accession number	P30550 (Sequence in FASTA format)
Description	Gastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesinreceptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain.
Post translational modification	N/A
Function	Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein Length	384 Amino acids
Molecular weight	43199
Domain Name	7tm_1
References	1  PubMed abstract 1655761 2  PubMed abstract 11245983 3  PubMed abstract 15489334
Hormone	P07492   Detail in HMRbase
Gene ID	2925
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 102

HMRbase accession number	21007
Swiss-prot Accession number	P30559 (Sequence in FASTA format)
Description	Oxytocin receptor (OT-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system.
Protein Length	389 Amino acids
Molecular weight	42772
Domain Name	7tm_1
References	1  PubMed abstract 1313946 2   Kimura T., Tanizawa O., Mori K., Brownstein M.J., Okayama H.; Nature 357:176-176(1992). 3   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 7798245 5  PubMed abstract 1313946 6   Kimura T., Tanizawa O., Mori K., Brownstein M.J., Okayama H.; Nature 357:176-176(1992). 7   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 8  PubMed abstract 7798245
Hormone	P01178   Detail in HMRbase
Gene ID	5021
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 103

HMRbase accession number	21010
Swiss-prot Accession number	P30872 (Sequence in FASTA format)
Description	Somatostatin receptor type 1 (SS1R) (SRIF-2).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.
Post translational modification	N/A
Function	Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
Protein Length	391 Amino acids
Molecular weight	42686
Domain Name	7tm_1
References	1  PubMed abstract 1346068 2   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 15489334 4  PubMed abstract 10734105 5  PubMed abstract 1346068 6   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 15489334 8  PubMed abstract 10734105
Hormone	P61278   Detail in HMRbase
Gene ID	6751
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 104

HMRbase accession number	21012
Swiss-prot Accession number	P30874 (Sequence in FASTA format)
Description	Somatostatin receptor type 2 (SS2R) (SRIF-1).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.
Post translational modification	N/A
Function	Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.
Protein Length	369 Amino acids
Molecular weight	41333
Domain Name	7tm_1
References	1  PubMed abstract 1346068 2  PubMed abstract 10619399 3   Kopatz S.A., Aronstam R.S., Sharma S.V.; "Isolation of complete coding sequence for somatostatin receptor 2(SSTR2)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 4   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 5   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 15489334 7  PubMed abstract 8386508 8  PubMed abstract 10551867 9  PubMed abstract 1346068 10  PubMed abstract 10619399 11   Kopatz S.A., Aronstam R.S., Sharma S.V.; "Isolation of complete coding sequence for somatostatin receptor 2(SSTR2)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 12   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 13   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 14  PubMed abstract 15489334 15  PubMed abstract 8386508 16  PubMed abstract 10551867 17  PubMed abstract 1346068 18  PubMed abstract 10619399 19   Kopatz S.A., Aronstam R.S., Sharma S.V.; "Isolation of complete coding sequence for somatostatin receptor 2(SSTR2)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 20   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 21   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 22  PubMed abstract 15489334 23  PubMed abstract 8386508 24  PubMed abstract 10551867
Hormone	P61278   Detail in HMRbase
Gene ID	6752
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 105

HMRbase accession number	21018
Swiss-prot Accession number	P30968 (Sequence in FASTA format)
Description	Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Pituitary, ovary, testis, breast and prostate but not in liver and spleen.
Post translational modification	N/A
Function	Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act a an inhibitor of GnRH-R signaling.
Protein Length	328 Amino acids
Molecular weight	37731
Domain Name	7tm_1
References	1  PubMed abstract 1333190 2  PubMed abstract 8386108 3  PubMed abstract 7534732 4  PubMed abstract 9272108 5  PubMed abstract 9259321 6   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 15489334 8  PubMed abstract 10366411 9  PubMed abstract 9371856 10  PubMed abstract 9425890 11  PubMed abstract 10022417 12  PubMed abstract 10084584 13  PubMed abstract 10523035 14  PubMed abstract 11397842 15  PubMed abstract 11318785 16  PubMed abstract 11397871 17  PubMed abstract 11994356 18  PubMed abstract 12679486
Hormone	O43555   Detail in HMRbase    P01148   Detail in HMRbase    Q6X4W1   Detail in HMRbase
Gene ID	2798
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 106

HMRbase accession number	21020
Swiss-prot Accession number	P30988 (Sequence in FASTA format)
Description	Calcitonin receptor precursor (CT-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.
Protein Length	490 Amino acids
Molecular weight	57303
Domain Name	7tm_2  HRM
References	1  PubMed abstract 1331173 2  PubMed abstract 8078488 3  PubMed abstract 7588285 4  PubMed abstract 8143880 5  PubMed abstract 10570950 6   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 12853948 8  PubMed abstract 15489334 9  PubMed abstract 15340161 10  PubMed abstract 7720653 11  PubMed abstract 7733946 12  PubMed abstract 15086532 13  PubMed abstract 9817931 14  PubMed abstract 1331173 15  PubMed abstract 8078488 16  PubMed abstract 7588285 17  PubMed abstract 8143880 18  PubMed abstract 10570950 19   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 20  PubMed abstract 12853948 21  PubMed abstract 15489334 22  PubMed abstract 15340161 23  PubMed abstract 7720653 24  PubMed abstract 7733946 25  PubMed abstract 15086532 26  PubMed abstract 9817931
Hormone	P01258   Detail in HMRbase
Gene ID	799
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 107

HMRbase accession number	21021
Swiss-prot Accession number	P31391 (Sequence in FASTA format)
Description	Somatostatin receptor type 4 (SS4R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.
Post translational modification	N/A
Function	Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.
Protein Length	388 Amino acids
Molecular weight	41895
Domain Name	7tm_1
References	1  PubMed abstract 8512564 2  PubMed abstract 8483934 3  PubMed abstract 8373420 4  PubMed abstract 8100352 5   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 11780052 7  PubMed abstract 15489334 8  PubMed abstract 8512564 9  PubMed abstract 8483934 10  PubMed abstract 8373420 11  PubMed abstract 8100352 12   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. 13  PubMed abstract 11780052 14  PubMed abstract 15489334
Hormone	P61278   Detail in HMRbase
Gene ID	6754
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 108

HMRbase accession number	21026
Swiss-prot Accession number	P32238 (Sequence in FASTA format)
Description	Cholecystokinin type A receptor (CCK-A receptor) (CCK-AR)(Cholecystokinin-1 receptor) (CCK1-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein Length	428 Amino acids
Molecular weight	47841
Domain Name	N/A
References	1  PubMed abstract 8503909 2  PubMed abstract 8343165 3  PubMed abstract 7557108 4  PubMed abstract 10682840 5   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 15489334 7  PubMed abstract 10555959 8  PubMed abstract 11300760 9  PubMed abstract 8503909 10  PubMed abstract 8343165 11  PubMed abstract 7557108 12  PubMed abstract 10682840 13   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 14  PubMed abstract 15489334 15  PubMed abstract 10555959 16  PubMed abstract 11300760
Hormone	P06307   Detail in HMRbase
Gene ID	886
PDB ID	1D6G   1HZN   1PB2
Drugpedia	wiki
Comments

Search Result - 109

HMRbase accession number	21027
Swiss-prot Accession number	P32239 (Sequence in FASTA format)
Description	Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR)(Cholecystokinin-2 receptor) (CCK2-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein Length	447 Amino acids
Molecular weight	48419
Domain Name	7tm_1
References	1  PubMed abstract 7681836 2  PubMed abstract 1280419 3  PubMed abstract 8415658 4  PubMed abstract 8349705 5   Tate S.N., Gray J., Denyer J., Stolz M., Foord S., Lee M.G.; Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases. 6   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 7   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 8  PubMed abstract 11926817 9  PubMed abstract 7681836 10  PubMed abstract 1280419 11  PubMed abstract 8415658 12  PubMed abstract 8349705 13   Tate S.N., Gray J., Denyer J., Stolz M., Foord S., Lee M.G.; Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases. 14   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 15   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 16  PubMed abstract 11926817
Hormone	P01350   Detail in HMRbase    P06307   Detail in HMRbase
Gene ID	887
PDB ID	1L4T
Drugpedia	wiki
Comments

Search Result - 110

HMRbase accession number	21029
Swiss-prot Accession number	P32745 (Sequence in FASTA format)
Description	Somatostatin receptor type 3 (SS3R) (SSR-28).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein (By similarity). Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Brain, pituitary and pancreas.
Post translational modification	Phosphorylated. Phosphorylation increases upon somatostatin binding (By similarity).
Function	Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
Protein Length	418 Amino acids
Molecular weight	45847
Domain Name	7tm_1
References	1  PubMed abstract 1337145 2  PubMed abstract 8097479 3   Rasch A.C., Boehnke C., Petersenn S.; "The human somatostatin receptor subtype 3 contains an upstream exonin the 5'-untranslated region: functional promoter studies."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 4   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 15461802 6  PubMed abstract 10591208 7  PubMed abstract 15489334 8  PubMed abstract 1337145 9  PubMed abstract 8097479 10   Rasch A.C., Boehnke C., Petersenn S.; "The human somatostatin receptor subtype 3 contains an upstream exonin the 5'-untranslated region: functional promoter studies."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 11   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 12  PubMed abstract 15461802 13  PubMed abstract 10591208 14  PubMed abstract 15489334 15  PubMed abstract 1337145 16  PubMed abstract 8097479 17   Rasch A.C., Boehnke C., Petersenn S.; "The human somatostatin receptor subtype 3 contains an upstream exonin the 5'-untranslated region: functional promoter studies."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 18   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 19  PubMed abstract 15461802 20  PubMed abstract 10591208 21  PubMed abstract 15489334
Hormone	P61278   Detail in HMRbase
Gene ID	6753
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 111

HMRbase accession number	21031
Swiss-prot Accession number	P34981 (Sequence in FASTA format)
Description	Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberinreceptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Protein Length	398 Amino acids
Molecular weight	45085
Domain Name	7tm_1
References	1  PubMed abstract 8395824 2  PubMed abstract 8396925 3  PubMed abstract 8243797 4  PubMed abstract 7918619 5  PubMed abstract 8703031 6   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 15489334 8  PubMed abstract 9886052 9  PubMed abstract 8770906 10  PubMed abstract 8395824 11  PubMed abstract 8396925 12  PubMed abstract 8243797 13  PubMed abstract 7918619 14  PubMed abstract 8703031 15   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases. 16  PubMed abstract 15489334 17  PubMed abstract 9886052 18  PubMed abstract 8770906
Hormone	P20396   Detail in HMRbase
Gene ID	7201
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 112

HMRbase accession number	21034
Swiss-prot Accession number	P34998 (Sequence in FASTA format)
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1)(Corticotropin-releasing hormone receptor 1) (CRH-R 1).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe.
Post translational modification	C-terminal Ser or Thr residues may be phosphorylated.
Function	This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Protein Length	444 Amino acids
Molecular weight	50719
Domain Name	7tm_2  HRM
References	1  PubMed abstract 7692441 2  PubMed abstract 8243652 3  PubMed abstract 9757017 4  PubMed abstract 7811272 5  PubMed abstract 10598591 6   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 11425856
Hormone	P06850   Detail in HMRbase
Gene ID	1394
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 113

HMRbase accession number	21036
Swiss-prot Accession number	P35346 (Sequence in FASTA format)
Description	Somatostatin receptor type 5 (SS5R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary.
Post translational modification	N/A
Function	Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
Protein Length	364 Amino acids
Molecular weight	39202
Domain Name	7tm_1
References	1  PubMed abstract 7908405 2  PubMed abstract 8373420 3  PubMed abstract 8078491 4  PubMed abstract 11157797 5  PubMed abstract 15616553 6  PubMed abstract 7908405 7  PubMed abstract 8373420 8  PubMed abstract 8078491 9  PubMed abstract 11157797 10  PubMed abstract 15616553
Hormone	P61278   Detail in HMRbase
Gene ID	6755
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 114

HMRbase accession number	21048
Swiss-prot Accession number	P47871 (Sequence in FASTA format)
Description	Glucagon receptor precursor (GL-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Protein Length	477 Amino acids
Molecular weight	54009
Domain Name	7tm_2  HRM
References	1  PubMed abstract 7507321 2  PubMed abstract 8144028 3  PubMed abstract 15489334 4  PubMed abstract 8020989 5  PubMed abstract 7589886 6  PubMed abstract 7507321 7  PubMed abstract 8144028 8  PubMed abstract 15489334 9  PubMed abstract 8020989 10  PubMed abstract 7589886 11  PubMed abstract 7507321 12  PubMed abstract 8144028 13  PubMed abstract 15489334 14  PubMed abstract 8020989 15  PubMed abstract 7589886
Hormone	P01275   Detail in HMRbase
Gene ID	2642
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 115

HMRbase accession number	21049
Swiss-prot Accession number	P47872 (Sequence in FASTA format)
Description	Secretin receptor precursor (SCT-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Protein Length	440 Amino acids
Molecular weight	50207
Domain Name	7tm_2  HRM
References	1  PubMed abstract 7864894 2  PubMed abstract 7612008 3  PubMed abstract 7700244 4   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 5   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	P09683   Detail in HMRbase
Gene ID	6344
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 116

HMRbase accession number	21052
Swiss-prot Accession number	P49683 (Sequence in FASTA format)
Description	Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10) (hGR3).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Only detected in the pituitary gland and in all cell types of pituitary adenomas.
Post translational modification	N/A
Function	Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.
Protein Length	370 Amino acids
Molecular weight	41107
Domain Name	7tm_1
References	1  PubMed abstract 8666380 2  PubMed abstract 9607765 3  PubMed abstract 11923475 4  PubMed abstract 15164054 5  PubMed abstract 15489334 6  PubMed abstract 10498338 7  PubMed abstract 11641419 8  PubMed abstract 8666380 9  PubMed abstract 9607765 10  PubMed abstract 11923475 11  PubMed abstract 15164054 12  PubMed abstract 15489334 13  PubMed abstract 10498338 14  PubMed abstract 11641419
Hormone	P81277   Detail in HMRbase
Gene ID	2834
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 117

HMRbase accession number	21064
Swiss-prot Accession number	Q01718 (Sequence in FASTA format)
Description	Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Melanocytes and corticoadrenal tissue.
Post translational modification	N/A
Function	Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase.
Protein Length	297 Amino acids
Molecular weight	33927
Domain Name	7tm_1
References	1  PubMed abstract 1325670 2   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 3   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15489334 5  PubMed abstract 8463333 6  PubMed abstract 15654338 7   Clark A.J.L., Weber A.; "Molecular insights into inherited ACTH resistance syndromes."; Trends Endocrinol. Metab. 5:209-214(1994). 8  PubMed abstract 8094489 9  PubMed abstract 8227361 10  PubMed abstract 8636348 11  PubMed abstract 10971458 12  PubMed abstract 12213892 13  PubMed abstract 1325670 14   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 15   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 16  PubMed abstract 15489334 17  PubMed abstract 8463333 18  PubMed abstract 15654338 19   Clark A.J.L., Weber A.; "Molecular insights into inherited ACTH resistance syndromes."; Trends Endocrinol. Metab. 5:209-214(1994). 20  PubMed abstract 8094489 21  PubMed abstract 8227361 22  PubMed abstract 8636348 23  PubMed abstract 10971458 24  PubMed abstract 12213892 25  PubMed abstract 1325670 26   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 27   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 28  PubMed abstract 15489334 29  PubMed abstract 8463333 30  PubMed abstract 15654338 31   Clark A.J.L., Weber A.; "Molecular insights into inherited ACTH resistance syndromes."; Trends Endocrinol. Metab. 5:209-214(1994). 32  PubMed abstract 8094489 33  PubMed abstract 8227361 34  PubMed abstract 8636348 35  PubMed abstract 10971458 36  PubMed abstract 12213892
Hormone	P01189   Detail in HMRbase
Gene ID	4158
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 118

HMRbase accession number	21065
Swiss-prot Accession number	Q01726 (Sequence in FASTA format)
Description	Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Melanocytes and corticoadrenal tissue.
Post translational modification	N/A
Function	Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Protein Length	317 Amino acids
Molecular weight	34706
Domain Name	7tm_1
References	1  PubMed abstract 1325670 2  PubMed abstract 8463333 3  PubMed abstract 1516719 4  PubMed abstract 8706868 5  PubMed abstract 10101176 6  PubMed abstract 11442765 7   Smith A.G., Box N.F., Marks L., Chen W., Sturm R.A.; "Complete sequence and characterization of the human melanocortin 1receptor locus: a study of promoter region polymorphism."; Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases. 8  PubMed abstract 11707265 9   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 10   Rieder M.J., Armel T.Z., Carrington D.P., Ozuna M., Kuldanek S.A.,Toth E.J., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases. 11  PubMed abstract 15489334 12  PubMed abstract 9640562 13  PubMed abstract 7581459 14  PubMed abstract 8894704 15  PubMed abstract 9302268 16  PubMed abstract 8990005 17  PubMed abstract 9571181 18  PubMed abstract 9665397 19  PubMed abstract 1325670 20  PubMed abstract 8463333 21  PubMed abstract 1516719 22  PubMed abstract 8706868 23  PubMed abstract 10101176 24  PubMed abstract 11442765 25   Smith A.G., Box N.F., Marks L., Chen W., Sturm R.A.; "Complete sequence and characterization of the human melanocortin 1receptor locus: a study of promoter region polymorphism."; Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases. 26  PubMed abstract 11707265 27   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 28   Rieder M.J., Armel T.Z., Carrington D.P., Ozuna M., Kuldanek S.A.,Toth E.J., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases. 29  PubMed abstract 15489334 30  PubMed abstract 9640562 31  PubMed abstract 7581459 32  PubMed abstract 8894704 33  PubMed abstract 9302268 34  PubMed abstract 8990005 35  PubMed abstract 9571181 36  PubMed abstract 9665397
Hormone	P01189   Detail in HMRbase
Gene ID	4157
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 119

HMRbase accession number	21069
Swiss-prot Accession number	Q02643 (Sequence in FASTA format)
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor)(GRF receptor) (GRFR).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	Pituitary gland.
Post translational modification	N/A
Function	Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
Protein Length	423 Amino acids
Molecular weight	47402
Domain Name	7tm_2  HRM
References	1  PubMed abstract 1333056 2  PubMed abstract 7680413 3   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 4   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 12853948 6   Tang J., Collu R.; "The structure of the gene coding for human growth hormone releasinghormone."; Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 11232012 8  PubMed abstract 10084571 9  PubMed abstract 12534354
Hormone	P01286   Detail in HMRbase    Q9UBU3   Detail in HMRbase
Gene ID	2692
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 120

HMRbase accession number	21071
Swiss-prot Accession number	Q03431 (Sequence in FASTA format)
Description	Parathyroid hormone/parathyroid hormone-related peptide receptorprecursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	Expressed in most tissues. Most abundant in kidney, bone and liver.
Post translational modification	N/A
Function	This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Protein Length	593 Amino acids
Molecular weight	66361
Domain Name	7tm_2  HRM
References	1  PubMed abstract 8386612 2  PubMed abstract 8397094 3  PubMed abstract 7745008 4   Levine M.A.; "Characterization of cDNA and genomic DNA encoding the human PTH/PTHrPreceptor."; Submitted (NOV-1994) to the EMBL/GenBank/DDBJ databases. 5   King M.M., Aronstam R.S., Sharma S.V.; "Isolation of cDNA coding for parathyroid hormone receptor 1(PTHR1)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 15489334 7  PubMed abstract 10913300 8  PubMed abstract 9737850 9  PubMed abstract 7701349 10  PubMed abstract 8703170 11  PubMed abstract 9178745 12  PubMed abstract 9745456 13  PubMed abstract 10487664 14  PubMed abstract 11850620 15  PubMed abstract 15523647 16  PubMed abstract 8386612 17  PubMed abstract 8397094 18  PubMed abstract 7745008 19   Levine M.A.; "Characterization of cDNA and genomic DNA encoding the human PTH/PTHrPreceptor."; Submitted (NOV-1994) to the EMBL/GenBank/DDBJ databases. 20   King M.M., Aronstam R.S., Sharma S.V.; "Isolation of cDNA coding for parathyroid hormone receptor 1(PTHR1)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 21  PubMed abstract 15489334 22  PubMed abstract 10913300 23  PubMed abstract 9737850 24  PubMed abstract 7701349 25  PubMed abstract 8703170 26  PubMed abstract 9178745 27  PubMed abstract 9745456 28  PubMed abstract 10487664 29  PubMed abstract 11850620 30  PubMed abstract 15523647
Hormone	P01270   Detail in HMRbase
Gene ID	5745
PDB ID	1BL1   1ET2   1ET3   3C4M
Drugpedia	wiki
Comments

Search Result - 121

HMRbase accession number	21073
Swiss-prot Accession number	Q13324 (Sequence in FASTA format)
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2)(Corticotropin-releasing hormone receptor 2) (CRH-R 2).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Protein Length	411 Amino acids
Molecular weight	47688
Domain Name	7tm_2  HRM
References	1  PubMed abstract 8536644 2   Kostich W.A., Chen A., Sperle K., Horlick R.A., Patterson J.,Hyde T.M., Largent B.L.; "Molecular cloning of the human CRH2B receptor isoform: divergencefrom the rodent isoform in sequence and expression pattern."; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 9717834 4   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 5   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 12853948 7  PubMed abstract 15489334 8  PubMed abstract 9199241 9  PubMed abstract 8536644 10   Kostich W.A., Chen A., Sperle K., Horlick R.A., Patterson J.,Hyde T.M., Largent B.L.; "Molecular cloning of the human CRH2B receptor isoform: divergencefrom the rodent isoform in sequence and expression pattern."; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases. 11  PubMed abstract 9717834 12   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 13   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 14  PubMed abstract 12853948 15  PubMed abstract 15489334 16  PubMed abstract 9199241
Hormone	P06850   Detail in HMRbase
Gene ID	1395
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 122

HMRbase accession number	21074
Swiss-prot Accession number	Q16671 (Sequence in FASTA format)
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30)(Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIStype II receptor) (MISRII) (MRII).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; single-pass type I membrane protein
Developmental Stage	N/A
Similarity	Belongs to the Ser/Thr protein kinase family. TGFB receptor subfamily. Contains 1 protein kinase domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Protein Length	573 Amino acids
Molecular weight	62750
Domain Name	Pkinase  Pkinase_Tyr
References	1  PubMed abstract 7493017 2  PubMed abstract 7488027 3  PubMed abstract 10589763 4  PubMed abstract 15489334 5  PubMed abstract 8872466 6  PubMed abstract 11549681
Hormone	P03971   Detail in HMRbase
Gene ID	269
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 123

HMRbase accession number	21157
Swiss-prot Accession number	Q8TDU9 (Sequence in FASTA format)
Description	Relaxin-3 receptor 2 (Relaxin family peptide receptor 4) (G-proteincoupled receptor 100) (GPCR142).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed in a broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon.
Post translational modification	N/A
Function	Receptor for relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation.
Protein Length	374 Amino acids
Molecular weight	41141
Domain Name	7tm_1
References	1  PubMed abstract 14522967 2  PubMed abstract 14623098 3  PubMed abstract 14530218 4   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 12044878 6  PubMed abstract 16710414 7  PubMed abstract 15489334
Hormone	Q8WXF3   Detail in HMRbase
Gene ID	339403
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 124

HMRbase accession number	21160
Swiss-prot Accession number	Q8WXD0 (Sequence in FASTA format)
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-richrepeat-containing G-protein coupled receptor 8) (G-protein coupledreceptor affecting testicular descent) (G-protein coupled receptor106).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family. Contains 1 LDL-receptor class A domain. Contains 10 LRR (leucine-rich) repeats.
Tissue Specificity	Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow.
Post translational modification	N/A
Function	Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).
Protein Length	754 Amino acids
Molecular weight	86453
Domain Name	LRR_1  Ldl_recept_a  7tm_1
References	1  PubMed abstract 11809971 2  PubMed abstract 12217959
Hormone	P04090   Detail in HMRbase    P04808   Detail in HMRbase    Q8WXF3   Detail in HMRbase
Gene ID	122042
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 125

HMRbase accession number	21170
Swiss-prot Accession number	Q969V1 (Sequence in FASTA format)
Description	Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCHR-2)(MCH-R2) (MCH2R) (MCH-2R) (MCH2) (G-protein coupled receptor 145)(GPRv17).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Specifically expressed in the brain, with highest levels in cerebral cortex, hippocampus and amygdala. No expression detected in the cerebellum, thalamus or hypothalamus.
Post translational modification	N/A
Function	Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.
Protein Length	340 Amino acids
Molecular weight	38849
Domain Name	7tm_1
References	1  PubMed abstract 11355873 2  PubMed abstract 11404457 3  PubMed abstract 11459838 4  PubMed abstract 11274220 5   Kurama T., Matsumoto S., Takasaki J., Terai K., Matsumoto M.,Kamohara M., Saito T., Soga T., Saito Y., Oda T., Masuho Y.,Furuichi K.; "Molecular characterization of a novel melanin-concentrating hormonereceptor: evidence of its expression in lateral hypothalamus."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. 6   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 7  PubMed abstract 14574404 8  PubMed abstract 15489334 9  PubMed abstract 15340116 10  PubMed abstract 11355873 11  PubMed abstract 11404457 12  PubMed abstract 11459838 13  PubMed abstract 11274220 14   Kurama T., Matsumoto S., Takasaki J., Terai K., Matsumoto M.,Kamohara M., Saito T., Soga T., Saito Y., Oda T., Masuho Y.,Furuichi K.; "Molecular characterization of a novel melanin-concentrating hormonereceptor: evidence of its expression in lateral hypothalamus."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. 15   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 16  PubMed abstract 14574404 17  PubMed abstract 15489334 18  PubMed abstract 15340116
Hormone	P20382   Detail in HMRbase    Q16048   Detail in HMRbase    Q9BQD1   Detail in HMRbase
Gene ID	84539
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 126

HMRbase accession number	21171
Swiss-prot Accession number	Q96P88 (Sequence in FASTA format)
Description	Gonadotropin-releasing hormone II receptor (Type II GnRH receptor)(GnRH-II-R).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed in many tissues.
Post translational modification	Phosphorylated on the C-terminal cytoplasmic tail (Probable).
Function	Receptor for gonadotropin releasing hormone II (GnRH II). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (Potential).
Protein Length	379 Amino acids
Molecular weight	41630
Domain Name	7tm_1
References	1  PubMed abstract 11707068 2  PubMed abstract 11861490
Hormone	O43555   Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 127

HMRbase accession number	21174
Swiss-prot Accession number	Q99705 (Sequence in FASTA format)
Description	Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Somatostatin receptor-like protein) (SLC-1).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart.
Post translational modification	N/A
Function	Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.
Protein Length	422 Amino acids
Molecular weight	45963
Domain Name	7tm_1
References	1  PubMed abstract 10441476 2  PubMed abstract 15941924 3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15461802 5   King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 6  PubMed abstract 10591208 7  PubMed abstract 15489334 8  PubMed abstract 8977118 9  PubMed abstract 10421367 10  PubMed abstract 15166293 11  PubMed abstract 15340116
Hormone	P20382   Detail in HMRbase    Q16048   Detail in HMRbase    Q9BQD1   Detail in HMRbase
Gene ID	2847
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 128

HMRbase accession number	21187
Swiss-prot Accession number	Q9HBX9 (Sequence in FASTA format)
Description	Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-richrepeat-containing G-protein coupled receptor 7).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family. Contains 1 LDL-receptor class A domain. Contains 10 LRR (leucine-rich) repeats.
Tissue Specificity	Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.
Post translational modification	N/A
Function	Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
Protein Length	757 Amino acids
Molecular weight	86993
Domain Name	LRR_1  7tm_1  Ldl_recept_a
References	1  PubMed abstract 10935549 2  PubMed abstract 11517286 3  PubMed abstract 12506116
Hormone	P04090   Detail in HMRbase    P04808   Detail in HMRbase    Q8WXF3   Detail in HMRbase
Gene ID	59350
PDB ID	2JM4
Drugpedia	wiki
Comments

Search Result - 129

HMRbase accession number	21193
Swiss-prot Accession number	Q9NSD7 (Sequence in FASTA format)
Description	Relaxin-3 receptor 1 (RLN3 receptor 1) (Relaxin family peptidereceptor 3) (Somatostatin- and angiotensin-like peptide receptor) (Gprotein-coupled receptor SALPR) (GPCR135).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
Post translational modification	N/A
Function	Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Protein Length	469 Amino acids
Molecular weight	51124
Domain Name	N/A
References	1  PubMed abstract 10806363 2   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 14522968 4  PubMed abstract 15489334
Hormone	Q8WXF3   Detail in HMRbase
Gene ID	51289
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 130

HMRbase accession number	21210
Swiss-prot Accession number	P10275 (Sequence in FASTA format)
Description	RecName: Androgen receptor;Alternative Name: Dihydrotestosterone receptor;Alternative Name: Nuclear receptor subfamily 3 group C member 4;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	Sumoylated on Lys-386 (major) and Lys-520. Phosphorylated in prostate cancer cells in response to several growth factors including EGF. Phosphorylation is induced by c-Src kinase (CSK). Tyr-534 is one of the major phosphorylation sites and an increase in phosphorylation and Src kinase activity is associated with prostate cancer progression.
Function	Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3.
Protein Length	919 Amino acids
Molecular weight	98989
Domain Name	Androgen_recep  Hormone_recep  zf-C4
References	1  PubMed abstract 3216866 2  PubMed abstract 2594783 3  PubMed abstract 2342476 4  PubMed abstract 3174628 5  PubMed abstract 2911578 6  PubMed abstract 2293020 7  PubMed abstract 15489334 8  PubMed abstract 2917688 9  PubMed abstract 3353726 10  PubMed abstract 3377788 11  PubMed abstract 2546571 12  PubMed abstract 3353727 13  PubMed abstract 1775137 14  PubMed abstract 1561105 15  PubMed abstract 9096391 16  PubMed abstract 10332029 17  PubMed abstract 10075738 18  PubMed abstract 10383460 19  PubMed abstract 10400640 20  PubMed abstract 10625666 21  PubMed abstract 10930412 22  PubMed abstract 11121022 23  PubMed abstract 12361945 24  PubMed abstract 12415108 25  PubMed abstract 14609956 26  PubMed abstract 14664718 27  PubMed abstract 12612053 28  PubMed abstract 16027218 29  PubMed abstract 16051670 30  PubMed abstract 17045208 31  PubMed abstract 17550981 32  PubMed abstract 10840043 33  PubMed abstract 11906285 34  PubMed abstract 15525515 35  PubMed abstract 15563469 36  PubMed abstract 16129672 37  PubMed abstract 16641486 38  PubMed abstract 18007036 39  PubMed abstract 17311914 40  PubMed abstract 17591767 41  PubMed abstract 17711855 42  PubMed abstract 17911242 43  PubMed abstract 1458719 44  PubMed abstract 8339746 45  PubMed abstract 8240973 46  PubMed abstract 7937057 47  PubMed abstract 7626493 48  PubMed abstract 9016528 49  PubMed abstract 2260966 50  PubMed abstract 2082179 51  PubMed abstract 1856263 52  PubMed abstract 1999491 53  PubMed abstract 2010552 54  PubMed abstract 2062380 55  PubMed abstract 1609793 56  PubMed abstract 1424203 57  PubMed abstract 1426313 58  PubMed abstract 1487249 59  PubMed abstract 1307250 60  PubMed abstract 1569163 61  PubMed abstract 1464650 62  PubMed abstract 1430233 63  PubMed abstract 1562539 64  PubMed abstract 1316540 65  PubMed abstract 1480178 66  PubMed abstract 1303262 67  PubMed abstract 1631125 68  PubMed abstract 8213813 69  PubMed abstract 8224266 70  PubMed abstract 8103398 71  PubMed abstract 8281139 72  PubMed abstract 8281140 73  PubMed abstract 8325932 74  PubMed abstract 8325950 75  PubMed abstract 8097257 76  PubMed abstract 8096390 77  PubMed abstract 8274409 78  PubMed abstract 8446106 79  PubMed abstract 8413310 80  PubMed abstract 8145761 81  PubMed abstract 7511268 82  PubMed abstract 8292051 83  PubMed abstract 8187068 84  PubMed abstract 7910529 85  PubMed abstract 7909256 86  PubMed abstract 8205256 87  PubMed abstract 8033918 88  PubMed abstract 8162033 89  PubMed abstract 7981687 90  PubMed abstract 7981689 91  PubMed abstract 8126121 92  PubMed abstract 7962294 93  PubMed abstract 8040309 94  PubMed abstract 7929841 95  PubMed abstract 7993455 96  PubMed abstract 7970939 97  PubMed abstract 8830623 98  PubMed abstract 7712463 99  PubMed abstract 7641413 100  PubMed abstract 7671849 101  PubMed abstract 7633398 102  PubMed abstract 7537149 103  PubMed abstract 7581399 104  PubMed abstract 7591265 105  PubMed abstract 7673412 106  PubMed abstract 8530589 107  PubMed abstract 7649358 108  PubMed abstract 7723794 109  PubMed abstract 8723113 110  PubMed abstract 9816170 111  PubMed abstract 9039340 112  PubMed abstract 9001799 113  PubMed abstract 8824883 114  PubMed abstract 8550758 115  PubMed abstract 8626869 116  PubMed abstract 8768864 117  PubMed abstract 8823308 118  PubMed abstract 8918984 119  PubMed abstract 8683794 120  PubMed abstract 8647313 121  PubMed abstract 8809734 122  PubMed abstract 8628719 123  PubMed abstract 8827083 124  PubMed abstract 9106550 125  PubMed abstract 9000575 126  PubMed abstract 9196614 127  PubMed abstract 9160185 128  PubMed abstract 9007482 129  PubMed abstract 8990010 130  PubMed abstract 9438000 131  PubMed abstract 9184448 132  PubMed abstract 9255042 133  PubMed abstract 9329414 134  PubMed abstract 9252933 135  PubMed abstract 9328206 136  PubMed abstract 9302173 137  PubMed abstract 9544375 138  PubMed abstract 9698822 139  PubMed abstract 9788719 140  PubMed abstract 9610419 141  PubMed abstract 9856504 142  PubMed abstract 9554754 143  PubMed abstract 9554755 144  PubMed abstract 9543136 145  PubMed abstract 9768671 146  PubMed abstract 9851768 147  PubMed abstract 9627582 148  PubMed abstract 9607727 149  PubMed abstract 10470409 150  PubMed abstract 10363963 151  PubMed abstract 10502786 152  PubMed abstract 10571951 153  PubMed abstract 10221692 154  PubMed abstract 10404311 155  PubMed abstract 10022458 156  PubMed abstract 10629558 157  PubMed abstract 10569618 158  PubMed abstract 10543676 159  PubMed abstract 10221770 160  PubMed abstract 10598582 161  PubMed abstract 10590024 162  PubMed abstract 10458483 163  PubMed abstract 10092153 164  PubMed abstract 10706109 165  PubMed abstract 10690872 166  PubMed abstract 11587068 167  PubMed abstract 11231320 168  PubMed abstract 11744994 169  PubMed abstract 15902657 170  PubMed abstract 16595706
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	367
PDB ID	1E3G   1GS4   1T5Z   1T63   1T65   1XJ7   1XOW   1XQ3   1Z95   2AM9   2AMA   2AMB   2AO6   2AX6   2AX7   2AX8   2AX9   2AXA   2HVC   2OZ7   2PIO   2PIP   2PIQ   2PIR   2PIT   2PIU   2PIV   2PIW   2PIX   2PKL   2PNU   2Q7I   2Q7J   2Q7K   2Q7L   2Z4J   3B5R   3B65   3B66   3B67   3B68
Drugpedia	wiki
Comments

Search Result - 131

HMRbase accession number	21221
Swiss-prot Accession number	P10589 (Sequence in FASTA format)
Description	RecName: COUP transcription factor 1;Alternative Name: COUP-TF I;Alternative Name: COUP-TF1;Alternative Name: Nuclear receptor subfamily 2 group F member 1;Alternative Name: V-ERBA-related protein EAR-3;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif.
Protein Length	423 Amino acids
Molecular weight	46156
Domain Name	Hormone_recep  zf-C4  zf-C4_C
References	1  PubMed abstract 2739739 2  PubMed abstract 2905047 3  PubMed abstract 15489334 4  PubMed abstract 10207062
Hormone	N/A
Gene ID	7025
PDB ID	2EBL
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 132

HMRbase accession number	21225
Swiss-prot Accession number	P24468 (Sequence in FASTA format)
Description	RecName: COUP transcription factor 2;Alternative Name: COUP-TF II;Alternative Name: COUP-TF2;Alternative Name: Nuclear receptor subfamily 2 group F member 2;Alternative Name: Apolipoprotein AI regulatory protein 1;ARP-1;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Found in all tissues.
Post translational modification	N/A
Function	Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.
Protein Length	414 Amino acids
Molecular weight	45571
Domain Name	Hormone_recep  zf-C4  zf-C4_C
References	1  PubMed abstract 1899293 2  PubMed abstract 15489334 3  PubMed abstract 1820218
Hormone	N/A
Gene ID	7026
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 133

HMRbase accession number	21245
Swiss-prot Accession number	P62508 (Sequence in FASTA format)
Description	RecName: Estrogen-related receptor gamma;Alternative Name: Estrogen receptor-related protein 3;Alternative Name: ERR gamma-2;Alternative Name: Nuclear receptor subfamily 3 group B member 3;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Probable)
Developmental Stage	Expressed at high levels in fetal brain and also in the fetal kidney, lung and liver.
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.
Post translational modification	N/A
Function	Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).
Protein Length	458 Amino acids
Molecular weight	51306
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 10072763 2  PubMed abstract 10048485 3  PubMed abstract 9676434 4  PubMed abstract 10707956 5  PubMed abstract 16710414 6  PubMed abstract 15489334 7  PubMed abstract 10428842 8  PubMed abstract 14651967 9  PubMed abstract 11864604 10  PubMed abstract 15161930 11  PubMed abstract 16307879 12  PubMed abstract 16990259
Hormone	Detail in HMRbase
Gene ID	2104
PDB ID	1KV6   1S9P   1S9Q   1TFC   1VJB   2E2R   2EWP   2GP7   2GPO   2GPP   2GPU   2GPV   2P7A   2P7G   2P7Z
Drugpedia	wiki
Comments

Search Result - 134

HMRbase accession number	21256
Swiss-prot Accession number	P03372 (Sequence in FASTA format)
Description	RecName: Estrogen receptor;ER;Alternative Name: Estradiol receptor;Alternative Name: ER-alpha;Alternative Name: Nuclear receptor subfamily 3 group A member 1;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	Phosphorylated by cyclin A/CDK2. Phosphorylation probably enhances transcriptional activity. Glycosylated; contains N-acetylglucosamine, probably O- linked.
Function	Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
Protein Length	595 Amino acids
Molecular weight	66216
Domain Name	Hormone_recep  Oest_recep  zf-C4
References	1  PubMed abstract 3753802 2  PubMed abstract 3754034 3  PubMed abstract 8600466 4  PubMed abstract 14574404 5  PubMed abstract 10619354 6  PubMed abstract 7916651 7  PubMed abstract 7476978 8  PubMed abstract 7539106 9  PubMed abstract 1577818 10  PubMed abstract 7838153 11  PubMed abstract 8999954 12  PubMed abstract 9627117 13  PubMed abstract 10428798 14  PubMed abstract 10567404 15  PubMed abstract 10359819 16  PubMed abstract 10825160 17  PubMed abstract 11358960 18  PubMed abstract 11113208 19  PubMed abstract 11971969 20  PubMed abstract 12415108 21  PubMed abstract 12917342 22  PubMed abstract 15047147 23  PubMed abstract 15199063 24  PubMed abstract 15940264 25  PubMed abstract 16603732 26  PubMed abstract 16427018 27  PubMed abstract 17658481 28  PubMed abstract 17347654 29  PubMed abstract 17998543 30  PubMed abstract 18187866 31  PubMed abstract 2247153 32  PubMed abstract 8221895 33  PubMed abstract 9338790 34  PubMed abstract 9600906 35  PubMed abstract 9875847 36  PubMed abstract 9619507 37  PubMed abstract 2792078 38  PubMed abstract 8961262 39  PubMed abstract 9195227 40  PubMed abstract 10942433 41  PubMed abstract 17224074
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	2099
PDB ID	1A52   1AKF   1ERE   1ERR   1G50   1GWQ   1GWR   1HCP   1HCQ   1L2I   1PCG   1QKT   1QKU   1R5K   1SJ0   1UOM   1X7E   1X7R   1XP1   1XP6   1XP9   1XPC   1XQC   1YIM   1YIN   1ZKY   2AYR   2B1V   2B1Z   2B23   2BJ4   2FAI   2G44   2G5O   2I0J   2IOG   2IOK   2JF9   2JFA   2OCF   2OUZ   2P15   2POG   2Q6J   2Q70   2QA6   2QA8   2QAB   2QE4   2QGT   2QGW
Drugpedia	wiki
Comments

Search Result - 135

HMRbase accession number	21281
Swiss-prot Accession number	Q92731 (Sequence in FASTA format)
Description	RecName: Estrogen receptor beta;ER-beta;Alternative Name: Nuclear receptor subfamily 3 group A member 2;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Isoform beta-1 is expressed in testis and ovary, and at a lower level in heart, brain, placenta, liver, skeletal muscle, spleen, thymus, prostate, colon, bone marrow, mammary gland and uterus. Also found in uterine bone, breast, and ovarian tumor cell lines, but not in colon and liver tumors. Isoform beta-2 is expressed in spleen, thymus, testis and ovary and at a lower level in skeletal muscle, prostate, colon, small intestine, leukocytes, bone marrow, mammary gland and uterus. Isoform beta-3 is found in testis. Isoform beta-4 is expressed in testis, and at a lower level in spleen, thymus, ovary, mammary gland and uterus. Isoform beta-5 is expressed in testis, placenta, skeletal muscle, spleen and leukocytes, and at a lower level in heart, lung, liver, kidney, pancreas, thymus, prostate, colon, small intestine, bone marrow, mammary gland and uterus. Not expressed in brain.
Post translational modification	N/A
Function	Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA- binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
Protein Length	530 Amino acids
Molecular weight	59216
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 9473491 2  PubMed abstract 9636657 3  PubMed abstract 8769313 4  PubMed abstract 9671811 5  PubMed abstract 9685228 6  PubMed abstract 15489334 7  PubMed abstract 10964723 8  PubMed abstract 9267036 9  PubMed abstract 9325313 10  PubMed abstract 10681503 11  PubMed abstract 11113208 12  PubMed abstract 11579095 13  PubMed abstract 12415108 14  PubMed abstract 15047147 15  PubMed abstract 14759258 16  PubMed abstract 15199063
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	2100
PDB ID	1L2J   1NDE   1QKM   1U3Q   1U3R   1U3S   1U9E   1X76   1X78   1X7B   1X7J   1YY4   1YYE   1ZAF   2FSZ   2GIU   2I0G   2JJ3   2NV7   2Z4B
Drugpedia	wiki
Comments

Search Result - 136

HMRbase accession number	21299
Swiss-prot Accession number	P04150 (Sequence in FASTA format)
Description	RecName: Glucocorticoid receptor;GR;Alternative Name: Nuclear receptor subfamily 3 group C member 1;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand, nuclear after ligand-binding
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart.
Post translational modification	Increased proteasome-mediated degradation in response to glucocorticoids. Phosphorylated in the absence of hormone; becomes hyperphosphorylated in the presence of glucocorticoid. The Ser- 203-phosphorylated form is mainly cytoplasmic, and the Ser-211- phosphorylated form is nuclear. Transcriptional activity correlates with the amount of phosphorylation at Ser-211. Sumoylated; this reduces transcription transactivation. Ubiquitinated; restricts glucocorticoid-mediated transcriptional signaling (By similarity).
Function	Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation (By similarity).
Protein Length	777 Amino acids
Molecular weight	85659
Domain Name	GCR  Hormone_recep  zf-C4
References	1  PubMed abstract 2867473 2  PubMed abstract 1707881 3  PubMed abstract 15372022 4  PubMed abstract 15489334 5  PubMed abstract 2026589 6  PubMed abstract 1958537 7  PubMed abstract 3841189 8  PubMed abstract 8358712 9  PubMed abstract 9154805 10  PubMed abstract 9590696 11  PubMed abstract 10477749 12  PubMed abstract 10566686 13  PubMed abstract 10902803 14  PubMed abstract 10866662 15  PubMed abstract 10639135 16  PubMed abstract 11555652 17  PubMed abstract 11238589 18  PubMed abstract 11435610 19  PubMed abstract 12144530 20  PubMed abstract 12000743 21  PubMed abstract 12415108 22  PubMed abstract 15265776 23  PubMed abstract 15211577 24  PubMed abstract 15941832 25  PubMed abstract 16478993 26  PubMed abstract 18691976 27  PubMed abstract 18669648 28  PubMed abstract 12151000 29  PubMed abstract 12686538 30  PubMed abstract 1704018 31  PubMed abstract 8358735 32  PubMed abstract 8445027 33  PubMed abstract 7683692 34  PubMed abstract 8316249 35  PubMed abstract 9150737 36  PubMed abstract 10391209 37  PubMed abstract 10898924 38  PubMed abstract 11589680 39  PubMed abstract 11344238 40  PubMed abstract 11701741 41  PubMed abstract 12351458 42  PubMed abstract 11932321 43  PubMed abstract 12050230 44  PubMed abstract 15276593 45  PubMed abstract 15292341
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	2908
PDB ID	1M2Z   1NHZ   1P93   3BQD   3CLD
Drugpedia	wiki
Comments

Search Result - 137

HMRbase accession number	21313
Swiss-prot Accession number	P41235 (Sequence in FASTA format)
Description	RecName: Hepatocyte nuclear factor 4-alpha;HNF-4-alpha;Alternative Name: Transcription factor HNF-4;Alternative Name: Nuclear receptor subfamily 2 group A member 1;Alternative Name: Transcription factor 14;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	Phosphorylated on tyrosine residue(s); phosphorylation is important for its DNA-binding activity. Phosphorylation may directly or indirectly play a regulatory role in the subnuclear distribution.
Function	Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine.
Protein Length	474 Amino acids
Molecular weight	52785
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 8964514 2  PubMed abstract 8622695 3  PubMed abstract 8945471 4  PubMed abstract 11780052 5  PubMed abstract 7926813 6  PubMed abstract 7568236 7  PubMed abstract 14982928 8  PubMed abstract 9313765 9  PubMed abstract 9243109 10  PubMed abstract 9267996 11  PubMed abstract 9449683
Hormone	N/A
Gene ID	3172
PDB ID	1PZL
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 138

HMRbase accession number	21318
Swiss-prot Accession number	Q14541 (Sequence in FASTA format)
Description	RecName: Hepatocyte nuclear factor 4-gamma;HNF-4-gamma;Alternative Name: Nuclear receptor subfamily 2 group A member 2;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Expressed in pancreas, kidney, small intestine and testis. Weakly expressed in colon. Not expressed in liver, skeletal muscle, lung, placenta, brain, heart, peripheral blood, ovary, prostate, thymus and spleen.
Post translational modification	N/A
Function	Transcription factor. Has a lower transcription activation potential than HNF4-alpha.
Protein Length	408 Amino acids
Molecular weight	45877
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 8622695 2  PubMed abstract 10512380 3  PubMed abstract 16421571 4  PubMed abstract 12220494
Hormone	N/A
Gene ID	N/A
PDB ID	1LV2
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 139

HMRbase accession number	21326
Swiss-prot Accession number	P08235 (Sequence in FASTA format)
Description	RecName: Mineralocorticoid receptor;MR;Alternative Name: Nuclear receptor subfamily 3 group C member 2;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Cytoplasmic and nuclear in the absence of ligand; nuclear after ligand-binding. When bound to HSD11B2, it is found associated with the endoplasmic reticulum membrane
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Ubiquitous. Highly expressed in distal tubules, convoluted tubules and cortical collecting duct in kidney, and in sweat glands. Detected at lower levels in cardiomyocytes, in epidermis and in colon enterocytes.
Post translational modification	Phosphorylated.
Function	Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Protein Length	984 Amino acids
Molecular weight	107067
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 3037703 2  PubMed abstract 11518808 3  PubMed abstract 15815621 4  PubMed abstract 9662404 5  PubMed abstract 1655735 6  PubMed abstract 7495694 7  PubMed abstract 9141514 8  PubMed abstract 9392437 9  PubMed abstract 9724527 10  PubMed abstract 10760050 11  PubMed abstract 10935545 12  PubMed abstract 11350956 13  PubMed abstract 15967794 14  PubMed abstract 16061183 15  PubMed abstract 15908963 16  PubMed abstract 10391210 17  PubMed abstract 11134129 18  PubMed abstract 10884226 19  PubMed abstract 12483305 20  PubMed abstract 12788847 21  PubMed abstract 16954160 22  PubMed abstract 16959974 23  PubMed abstract 16972228
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	4306
PDB ID	1Y9R   1YA3   2A3I   2AA2   2AA5   2AA6   2AA7   2AAX   2AB2   2ABI   2OAX
Drugpedia	wiki
Comments

Search Result - 140

HMRbase accession number	21339
Swiss-prot Accession number	P51843 (Sequence in FASTA format)
Description	RecName: Nuclear receptor subfamily 0 group B member 1;Alternative Name: Nuclear receptor DAX-1;Alternative Name: DSS-AHC critical region on the X chromosome protein 1;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR0 subfamily.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).
Protein Length	470 Amino acids
Molecular weight	51718
Domain Name	Hormone_recep
References	1  PubMed abstract 7990953 2  PubMed abstract 8675564 3  PubMed abstract 15489334 4  PubMed abstract 10713076 5  PubMed abstract 12482977 6  PubMed abstract 15589120 7  PubMed abstract 16146703 8  PubMed abstract 16709599 9  PubMed abstract 7990958 10  PubMed abstract 9003500 11  PubMed abstract 9360549 12  PubMed abstract 9063431 13  PubMed abstract 9415399 14  PubMed abstract 9529340 15  PubMed abstract 9486644 16  PubMed abstract 10323730 17  PubMed abstract 10341858 18  PubMed abstract 10675358 19  PubMed abstract 11113848 20  PubMed abstract 10848616 21  PubMed abstract 11748852 22  PubMed abstract 11443184 23  PubMed abstract 11788621 24  PubMed abstract 12629128 25  PubMed abstract 15800903
Hormone	Detail in HMRbase
Gene ID	190
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 141

HMRbase accession number	21346
Swiss-prot Accession number	Q15466 (Sequence in FASTA format)
Description	RecName: Nuclear receptor subfamily 0 group B member 2;Alternative Name: Orphan nuclear receptor SHP;Alternative Name: Small heterodimer partner;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR0 subfamily.
Tissue Specificity	Liver. Low levels of expression were detected in heart and pancreas.
Post translational modification	N/A
Function	Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts.
Protein Length	257 Amino acids
Molecular weight	28058
Domain Name	Hormone_recep
References	1  PubMed abstract 8650544 2  PubMed abstract 9603951 3  PubMed abstract 11136233 4  PubMed abstract 16710414 5  PubMed abstract 15489334 6  PubMed abstract 15723037
Hormone	N/A
Gene ID	8431
PDB ID	1YUC   2Z4J
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 142

HMRbase accession number	21349
Swiss-prot Accession number	P20393 (Sequence in FASTA format)
Description	RecName: Nuclear receptor subfamily 1 group D member 1;Alternative Name: V-erbA-related protein EAR-1;Alternative Name: Rev-erbA-alpha;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Expressed in all tissues and cell lines examined. Expressed at high levels in some squamous carcinoma cell lines.
Post translational modification	N/A
Function	Functions as a constitutive transcriptional repressor. Possible receptor for triiodothyronine.
Protein Length	614 Amino acids
Molecular weight	66805
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2539258 2  PubMed abstract 1971514 3  PubMed abstract 15489334 4  PubMed abstract 1850510 5  PubMed abstract 15302935 6  PubMed abstract 9660968
Hormone	N/A
Gene ID	9572
PDB ID	1A6Y   1EF6   1GA5   1HLZ
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 143

HMRbase accession number	21355
Swiss-prot Accession number	P55055 (Sequence in FASTA format)
Description	RecName: Oxysterols receptor LXR-beta;Alternative Name: Liver X receptor beta;Alternative Name: Nuclear orphan receptor LXR-beta;Alternative Name: Nuclear receptor subfamily 1 group H member 2;Alternative Name: Ubiquitously-expressed nuclear receptor;Alternative Name: Nuclear receptor NER;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Ubiquitous.
Post translational modification	N/A
Function	Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4).
Protein Length	461 Amino acids
Molecular weight	51102
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 7926814 2  PubMed abstract 14702039 3  PubMed abstract 15489334 4  PubMed abstract 12819202
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	7376
PDB ID	1P8D   1PQ6   1PQ9   1PQC   1UPV   1UPW
Drugpedia	wiki
Comments

Search Result - 144

HMRbase accession number	21359
Swiss-prot Accession number	Q13133 (Sequence in FASTA format)
Description	RecName: Oxysterols receptor LXR-alpha;Alternative Name: Liver X receptor alpha;Alternative Name: Nuclear orphan receptor LXR-alpha;Alternative Name: Nuclear receptor subfamily 1 group H member 3;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.
Post translational modification	N/A
Function	Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand- binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half- sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis.
Protein Length	447 Amino acids
Molecular weight	50396
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 7744246 2  PubMed abstract 15489334
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	10062
PDB ID	1UHL
Drugpedia	wiki
Comments

Search Result - 145

HMRbase accession number	21363
Swiss-prot Accession number	Q96RI1 (Sequence in FASTA format)
Description	RecName: Bile acid receptor;Alternative Name: Farnesoid X-activated receptor;Alternative Name: Farnesol receptor HRR-1;Alternative Name: Nuclear receptor subfamily 1 group H member 4;Alternative Name: Retinoid X receptor-interacting protein 14;RXR-interacting protein 14;
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Probable)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) and activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 within its gene locus.
Protein Length	486 Amino acids
Molecular weight	55914
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 12062799 2  PubMed abstract 10334992 3  PubMed abstract 10334993 4  PubMed abstract 12917342 5  PubMed abstract 15471871
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	9971
PDB ID	1OSH   1OSK   3BEJ
Drugpedia	wiki
Comments

Search Result - 146

HMRbase accession number	21366
Swiss-prot Accession number	O75469 (Sequence in FASTA format)
Description	RecName: Nuclear receptor subfamily 1 group I member 2;Alternative Name: Orphan nuclear receptor PXR;Alternative Name: Pregnane X receptor;Alternative Name: Orphan nuclear receptor PAR1;Alternative Name: Steroid and xenobiotic receptor;SXR
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Expressed in liver, colon and small intestine.
Post translational modification	N/A
Function	Orphan receptor; its natural ligand is probably pregnane. Binds to a response element in the CYP3A4 and ABCB1/MDR1 genes promoter. Activates its expression in response to a wide variety of endobiotics and xenobiotics.
Protein Length	434 Amino acids
Molecular weight	49762
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 9784494 2  PubMed abstract 9727070 3  PubMed abstract 9770465 4  PubMed abstract 11668216 5  PubMed abstract 15489334 6  PubMed abstract 11297522 7  PubMed abstract 12606758 8  PubMed abstract 11408620 9  PubMed abstract 15618712
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	8856
PDB ID	1ILG   1ILH   1M13   1NRL   1SKX   2O9I
Drugpedia	wiki
Comments

Search Result - 147

HMRbase accession number	21371
Swiss-prot Accession number	Q14994 (Sequence in FASTA format)
Description	RecName: Nuclear receptor subfamily 1 group I member 3;Alternative Name: Constitutive androstane receptor;CAR;Alternative Name: Constitutive activator of retinoid response;Constitutive active response;Alternative Name: Orphan nuclear receptor MB67
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Predominantly expressed in liver.
Post translational modification	N/A
Function	Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
Protein Length	352 Amino acids
Molecular weight	39942
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 8114692 2  PubMed abstract 15489334 3  PubMed abstract 8603043 4  PubMed abstract 15610735 5  PubMed abstract 15618763
Hormone	N/A
Gene ID	9970
PDB ID	1XV9   1XVP
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 148

HMRbase accession number	21377
Swiss-prot Accession number	P13056 (Sequence in FASTA format)
Description	RecName: Nuclear receptor subfamily 2 group C member 1;Alternative Name: Orphan nuclear receptor TR2;Alternative Name: Testicular receptor 2
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Orphan nuclear receptor. Represses transcription and binds DNA as a homodimer. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism (By similarity).
Protein Length	483 Amino acids
Molecular weight	53042
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 3421977 2  PubMed abstract 18669648
Hormone	N/A
Gene ID	7181
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 149

HMRbase accession number	21380
Swiss-prot Accession number	P49116 (Sequence in FASTA format)
Description	RecName: Nuclear receptor subfamily 2 group C member 2;Alternative Name: Orphan nuclear receptor TR4;Alternative Name: Testicular receptor 4;Alternative Name: Orphan nuclear receptor TAK1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Probable)
Developmental Stage	Transiently repressed during the meiotic phase of spermatogenesis.
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Orphan nuclear receptor. May regulate gene expression during the late phase of spermatogenesis.
Protein Length	596 Amino acids
Molecular weight	65414
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 7708055 2  PubMed abstract 8016112 3  PubMed abstract 12486131 4  PubMed abstract 18691976 5  PubMed abstract 18669648
Hormone	N/A
Gene ID	7182
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 150

HMRbase accession number	21384
Swiss-prot Accession number	Q9Y466 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 2 group E member 1;Alternative Name: Nuclear receptor TLX;Alternative Name: Protein tailless homolog;Tll;hTll
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Brain specific. Present in all brain sections tested, highest levels in the caudate nucleus and hippocampus, weakest levels in the thalamus.
Post translational modification	N/A
Function	Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half- site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development (By similarity).
Protein Length	385 Amino acids
Molecular weight	42589
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 9628820 2  PubMed abstract 11073974 3  PubMed abstract 14574404 4  PubMed abstract 15489334 5  PubMed abstract 18187866
Hormone	N/A
Gene ID	7101
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 151

HMRbase accession number	21388
Swiss-prot Accession number	Q9Y5X4 (Sequence in FASTA format)
Description	Photoreceptor-specific nuclear receptor;Alternative Name: Retina-specific nuclear receptor;Alternative Name: Nuclear receptor subfamily 2 group E member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Eye specific; found solely in the outer nuclear layer of the adult neurosensory retina, where the nuclei of cone and rod photoreceptors reside.
Post translational modification	N/A
Function	Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function.
Protein Length	410 Amino acids
Molecular weight	44692
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 10220376 2  PubMed abstract 10611353 3  PubMed abstract 17081983 4  PubMed abstract 11071390 5  PubMed abstract 10655056 6  PubMed abstract 12963616 7  PubMed abstract 15459973 8  PubMed abstract 17564971
Hormone	N/A
Gene ID	10002
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 152

HMRbase accession number	21392
Swiss-prot Accession number	P10588 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 2 group F member 6;Alternative Name: Orphan nuclear receptor EAR-2;Alternative Name: V-erbA-related protein EAR-2
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	404 Amino acids
Molecular weight	42979
Domain Name	Hormone_recep  zf-C4  zf-C4_C
References	1  PubMed abstract 2905047 2  PubMed abstract 15489334 3  PubMed abstract 15302935 4  PubMed abstract 18669648
Hormone	N/A
Gene ID	2063
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 153

HMRbase accession number	21397
Swiss-prot Accession number	P22736 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 4 group A member 1;Alternative Name: Orphan nuclear receptor HMR;Alternative Name: Early response protein NAK1;Alternative Name: TR3 orphan receptor;Alternative Name: ST-59
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Fetal muscle and adult liver, brain and thyroid.
Post translational modification	N/A
Function	Orphan nuclear receptor.
Protein Length	598 Amino acids
Molecular weight	64463
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2283997 2  PubMed abstract 2626032 3  PubMed abstract 15489334 4  PubMed abstract 1651101 5  PubMed abstract 15459248 6  PubMed abstract 18669648
Hormone	N/A
Gene ID	3164
PDB ID	2QW4
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 154

HMRbase accession number	21401
Swiss-prot Accession number	P43354 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 4 group A member 2;Alternative Name: Orphan nuclear receptor NURR1;Alternative Name: Immediate-early response protein NOT;Alternative Name: Transcriptionally-inducible nuclear receptor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Probable)
Developmental Stage	Rapidly and only very transiently expressed after cell activation, during the G0-G1 transition of the cell cycle.
Similarity	Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.
Post translational modification	N/A
Function	Probable nuclear receptor. May function as a general coactivator of gene transcription. Detection of the protein in the brain, indicates that it is not mandatorily associated with cell cycle progression.
Protein Length	598 Amino acids
Molecular weight	66591
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 7877627 2  PubMed abstract 10216262 3  PubMed abstract 10216261 4  PubMed abstract 15489334 5  PubMed abstract 7706727 6  PubMed abstract 17081983
Hormone	N/A
Gene ID	4929
PDB ID	1OVL
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 155

HMRbase accession number	21408
Swiss-prot Accession number	O00482 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 5 group A member 2;Alternative Name: Alpha-1-fetoprotein transcription factor;Alternative Name: Hepatocytic transcription factor;Alternative Name: B1-binding factor;hB1F;Alternative Name: CYP7A promoter-binding factor;Alternative Name: Liver receptor homolog 1;LRH-1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Probable)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR5 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in hepG2. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and hepG2 cells.
Post translational modification	N/A
Function	Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
Protein Length	541 Amino acids
Molecular weight	61331
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 9786908 2  PubMed abstract 10359768 3  PubMed abstract 11595170 4  PubMed abstract 9858833 5  PubMed abstract 15707893 6  PubMed abstract 16289203 7  PubMed abstract 15723037 8  PubMed abstract 15897460
Hormone	N/A
Gene ID	2494
PDB ID	1YOK   1YUC   1ZDU   2A66
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 156

HMRbase accession number	21411
Swiss-prot Accession number	Q15406 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 6 group A member 1;Alternative Name: Germ cell nuclear factor;GCNF;hGCNF;Alternative Name: Retinoid receptor-related testis-specific receptor;RTR;hRTR
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Probable)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR6 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Shows highest expression in the germ cells of the adult testis.
Post translational modification	N/A
Function	Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity).
Protein Length	480 Amino acids
Molecular weight	54383
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 8982251 2  PubMed abstract 9177477 3  PubMed abstract 9134503 4  PubMed abstract 9537518 5  PubMed abstract 9493564 6  PubMed abstract 15164053 7  PubMed abstract 15489334 8  PubMed abstract 12080054
Hormone	N/A
Gene ID	2649
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 157

HMRbase accession number	21418
Swiss-prot Accession number	Q07869 (Sequence in FASTA format)
Description	Peroxisome proliferator-activated receptor alpha;PPAR-alpha;Alternative Name: Nuclear receptor subfamily 1 group C member 1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Skeletal muscle, liver, heart and kidney.
Post translational modification	N/A
Function	Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.
Protein Length	468 Amino acids
Molecular weight	52225
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 7684926 2  PubMed abstract 7981125 3  PubMed abstract 8993548 4  PubMed abstract 15461802 5  PubMed abstract 10591208 6  PubMed abstract 9238002 7  PubMed abstract 10681503 8  PubMed abstract 11698662 9  PubMed abstract 11587644 10  PubMed abstract 11845213
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	5465
PDB ID	1I7G   1K7L   1KKQ   2NPA   2P54   2REW
Drugpedia	wiki
Comments

Search Result - 158

HMRbase accession number	21428
Swiss-prot Accession number	P37231 (Sequence in FASTA format)
Description	Peroxisome proliferator-activated receptor gamma;PPAR-gamma;Alternative Name: Nuclear receptor subfamily 1 group C member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Highest expression in adipose tissue. Lower in skeletal muscle, spleen, heart and liver. Also are detectable in placenta, lung and ovary.
Post translational modification	N/A
Function	Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis.
Protein Length	505 Amino acids
Molecular weight	57620
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 9065481 2  PubMed abstract 8702406 3  PubMed abstract 9144532 4  PubMed abstract 7787419 5  PubMed abstract 9356045 6  PubMed abstract 8706692 7  PubMed abstract 15489334 8  PubMed abstract 10681503 9  PubMed abstract 11971969 10  PubMed abstract 15047147 11  PubMed abstract 15687259 12  PubMed abstract 9813012 13  PubMed abstract 9744270 14  PubMed abstract 10882139 15  PubMed abstract 11698662 16  PubMed abstract 11587644 17  PubMed abstract 12672231 18  PubMed abstract 15258145 19  PubMed abstract 15056000 20  PubMed abstract 15974597 21  PubMed abstract 15976031 22  PubMed abstract 16919947 23  PubMed abstract 16451087 24  PubMed abstract 16640330 25  PubMed abstract 9425261 26  PubMed abstract 9753710 27  PubMed abstract 9806549 28  PubMed abstract 10407229 29  PubMed abstract 10523018 30  PubMed abstract 10394368 31  PubMed abstract 10622252 32  PubMed abstract 12453919 33  PubMed abstract 11788685 34  PubMed abstract 14569127 35  PubMed abstract 15356014 36  PubMed abstract 15562396
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	5468
PDB ID	1FM6   1FM9   1I7I   1K74   1KNU   1NYX   1PRG   1RDT   1WM0   1ZEO   1ZGY   2ATH   2F4B   2FVJ   2G0G   2G0H   2GTK   2HFP   2HWQ   2HWR   2I4J   2I4P   2I4Z   2OM9   2P4Y   2POB   2PRG   2Q59   2Q5P   2Q5S   2Q61   2Q6R   2Q6S   2QMV   3CS8   3CWD   3PRG   4PRG
Drugpedia	wiki
Comments

Search Result - 159

HMRbase accession number	21437
Swiss-prot Accession number	P06401 (Sequence in FASTA format)
Description	Progesterone receptor;PR;Alternative Name: Nuclear receptor subfamily 3 group C member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
Protein Length	933 Amino acids
Molecular weight	98981
Domain Name	Hormone_recep  Prog_receptor  zf-C4
References	1  PubMed abstract 2328727 2  PubMed abstract 3551956 3  PubMed abstract 11110801 4  PubMed abstract 12917342 5  PubMed abstract 16478993 6  PubMed abstract 17347654 7  PubMed abstract 18088087 8  PubMed abstract 9620806 9  PubMed abstract 15937332
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	5241
PDB ID	1A28   1E3K   1SQN   1SR7   1ZUC   2C7A   2OVH   2OVM
Drugpedia	wiki
Comments

Search Result - 160

HMRbase accession number	21449
Swiss-prot Accession number	P10276 (Sequence in FASTA format)
Description	Retinoic acid receptor alpha;RAR-alpha;Alternative Name: Nuclear receptor subfamily 1 group B member 1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	Phosphorylated. Phosphorylation does not change during cell cycle. Phosphorylation on Ser-77 is crucial for transcriptional activity (By similarity).
Function	This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression.
Protein Length	462 Amino acids
Molecular weight	50771
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2825036 2  PubMed abstract 8302850 3  PubMed abstract 10337631 4  PubMed abstract 15489334 5  PubMed abstract 2175878 6  PubMed abstract 2825025 7  PubMed abstract 8562957 8  PubMed abstract 12691149 9  PubMed abstract 9267036 10  PubMed abstract 10567404 11  PubMed abstract 11971969
Hormone	N/A
Gene ID	5914
PDB ID	1DKF   1DSZ
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 161

HMRbase accession number	21455
Swiss-prot Accession number	P10826 (Sequence in FASTA format)
Description	Retinoic acid receptor beta;RAR-beta;Alternative Name: Nuclear receptor subfamily 1 group B member 2;Alternative Name: RAR-epsilon;Alternative Name: HBV-activated protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Isoform Beta-1: Nucleus. Isoform Beta-2: Nucleus. Isoform Beta-4: Cytoplasm
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression.
Protein Length	455 Amino acids
Molecular weight	50489
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2836738 2  PubMed abstract 2825037 3  PubMed abstract 10411930 4  PubMed abstract 15489334 5  PubMed abstract 1663808 6  PubMed abstract 8275470 7  PubMed abstract 3014347 8  PubMed abstract 2170809 9  PubMed abstract 2833708 10  PubMed abstract 1321662 11  PubMed abstract 8383553 12  PubMed abstract 16959974
Hormone	N/A
Gene ID	5915
PDB ID	1HRA   1XAP
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 162

HMRbase accession number	21460
Swiss-prot Accession number	P13631 (Sequence in FASTA format)
Description	Retinoic acid receptor gamma;RAR-gamma;Alternative Name: Nuclear receptor subfamily 1 group B member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression.
Protein Length	454 Amino acids
Molecular weight	50342
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2546152 2  PubMed abstract 2172793 3  PubMed abstract 1849262 4  PubMed abstract 15489334 5  PubMed abstract 2157210 6  PubMed abstract 1320193 7  PubMed abstract 7501014 8  PubMed abstract 9501913 9  PubMed abstract 16959974
Hormone	N/A
Gene ID	5916
PDB ID	1EXA   1EXX   1FCX   1FCY   1FCZ   1FD0   2LBD   3LBD   4LBD
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 163

HMRbase accession number	21464
Swiss-prot Accession number	P35398 (Sequence in FASTA format)
Description	Nuclear receptor ROR-alpha;Alternative Name: Retinoid-related orphan receptor-alpha;Alternative Name: Nuclear receptor RZR-alpha;Alternative Name: Nuclear receptor subfamily 1 group F member 1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Probable)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Orphan nuclear receptor. Binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'.
Protein Length	556 Amino acids
Molecular weight	63036
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 7926749 2  PubMed abstract 7916608 3  PubMed abstract 15489334 4  PubMed abstract 16959974
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	6095
PDB ID	1N83   1S0X
Drugpedia	wiki
Comments

Search Result - 164

HMRbase accession number	21466
Swiss-prot Accession number	Q92753 (Sequence in FASTA format)
Description	Nuclear receptor ROR-beta;Alternative Name: Retinoid-related orphan receptor-beta;Alternative Name: Nuclear receptor RZR-beta;Alternative Name: Nuclear receptor subfamily 1 group F member 2
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Probable)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter (By similarity).
Protein Length	470 Amino acids
Molecular weight	53220
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15164053
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 165

HMRbase accession number	21469
Swiss-prot Accession number	P51449 (Sequence in FASTA format)
Description	Nuclear receptor ROR-gamma;Alternative Name: Retinoid-related orphan receptor-gamma;Alternative Name: Nuclear receptor RZR-gamma;Alternative Name: Nuclear receptor subfamily 1 group F member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (Probable)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Highly expressed in skeletal muscle.
Post translational modification	N/A
Function	Orphan nuclear receptor.
Protein Length	518 Amino acids
Molecular weight	58195
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 7811290 2  PubMed abstract 15489334
Hormone	N/A
Gene ID	6097
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 166

HMRbase accession number	21474
Swiss-prot Accession number	P19793 (Sequence in FASTA format)
Description	Retinoic acid receptor RXR-alpha;Alternative Name: Retinoid X receptor alpha;Alternative Name: Nuclear receptor subfamily 2 group B member 1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Highly expressed in liver, also found in lung, kidney and heart.
Post translational modification	Sumoylated on Lys-108; which negatively regulates transcriptional activity. Desumoylated specifically by SENP6.
Function	Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer (By similarity).
Protein Length	462 Amino acids
Molecular weight	50811
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2159111 2  PubMed abstract 1310260 3  PubMed abstract 9267036 4  PubMed abstract 10567404 5  PubMed abstract 11259580 6  PubMed abstract 15047147 7  PubMed abstract 14981089 8  PubMed abstract 16574651 9  PubMed abstract 16912044 10  PubMed abstract 7925381 11  PubMed abstract 7746322 12  PubMed abstract 7760929 13  PubMed abstract 9698548
Hormone	N/A
Gene ID	6256
PDB ID	1BY4   1DSZ   1FBY   1FM6   1FM9   1G1U   1G5Y   1K74   1LBD   1MV9   1MVC   1MZN   1R0N   1RDT   1RXR   1XLS   1XV9   1XVP   1YNW   2ACL   2NLL   2P1T   2P1U   2P1V
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 167

HMRbase accession number	21481
Swiss-prot Accession number	P28702 (Sequence in FASTA format)
Description	Retinoic acid receptor RXR-beta;Alternative Name: Retinoid X receptor beta;Alternative Name: Nuclear receptor subfamily 2 group B member 2
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Expressed in a variety of tumor cell lines.
Post translational modification	N/A
Function	Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA).
Protein Length	533 Amino acids
Molecular weight	56922
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 1310259 2  PubMed abstract 1330328 3  PubMed abstract 1315958 4  PubMed abstract 14574404 5  PubMed abstract 15489334 6  PubMed abstract 8381386 7  PubMed abstract 11782480
Hormone	N/A
Gene ID	6257
PDB ID	1H9U   1UHL
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 168

HMRbase accession number	21488
Swiss-prot Accession number	P48443 (Sequence in FASTA format)
Description	Retinoic acid receptor RXR-gamma;Alternative Name: Retinoid X receptor gamma;Alternative Name: Nuclear receptor subfamily 2 group B member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA) (By similarity).
Protein Length	463 Amino acids
Molecular weight	50871
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 16710414 2  PubMed abstract 15489334
Hormone	N/A
Gene ID	6258
PDB ID	2GL8
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 169

HMRbase accession number	21506
Swiss-prot Accession number	P11473 (Sequence in FASTA format)
Description	Vitamin D3 receptor;VDR;Alternative Name: 1,25-dihydroxyvitamin D3 receptor;Alternative Name: Nuclear receptor subfamily 1 group I member 1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Plays a central role in calcium homeostasis.
Protein Length	427 Amino acids
Molecular weight	48289
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2835767 2  PubMed abstract 1324736 3  PubMed abstract 9212063 4  PubMed abstract 15489334 5  PubMed abstract 1850412 6  PubMed abstract 9267036 7  PubMed abstract 10866662 8  PubMed abstract 10678179 9  PubMed abstract 11344298 10  PubMed abstract 11980721 11  PubMed abstract 15055995 12  PubMed abstract 15225774 13  PubMed abstract 15728261 14  PubMed abstract 16913708 15  PubMed abstract 2849209 16  PubMed abstract 8381803 17  PubMed abstract 1652893 18  PubMed abstract 2177843 19  PubMed abstract 8106618 20  PubMed abstract 8392085 21  PubMed abstract 7828346 22  PubMed abstract 8675579 23  PubMed abstract 8961271 24  PubMed abstract 9005998 25  PubMed abstract 15032981
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	7421
PDB ID	1DB1   1IE8   1IE9   1KB2   1KB4   1KB6   1S0Z   1S19   1TXI   1YNW   2HAM   2HAR   2HAS   2HB7   2HB8
Drugpedia	wiki
Comments

Search Result - 170

HMRbase accession number	21512
Swiss-prot Accession number	A1L4K5 (Sequence in FASTA format)
Description	NR1H4 protein;Nuclear receptor subfamily 1, group H, member 4, isoform CRA_b
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	476 Amino acids
Molecular weight	54862
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 171

HMRbase accession number	21513
Swiss-prot Accession number	A2A3I7 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 4, group A, member 3 (Nuclear receptor subfamily 4, group A, member 3, isoform CRA_a)
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	637 Amino acids
Molecular weight	69502
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	8013
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 172

HMRbase accession number	21514
Swiss-prot Accession number	A8K3H5 (Sequence in FASTA format)
Description	cDNA FLJ77492, highly similar to Human nuclear receptor hTAK1 (hTAK1) mRNA;Nuclear receptor subfamily 2, group C, member 2, isoform CRA_b
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	596 Amino acids
Molecular weight	65414
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 173

HMRbase accession number	21515
Swiss-prot Accession number	A8K3J9 (Sequence in FASTA format)
Description	cDNA FLJ78537;Nuclear receptor subfamily 1, group H, member 3, isoform CRA_e
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	447 Amino acids
Molecular weight	50396
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	10062
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 174

HMRbase accession number	21516
Swiss-prot Accession number	A8K5K4 (Sequence in FASTA format)
Description	cDNA FLJ77543, highly similar to Homo sapiens nuclear receptor subfamily 2, group C, member 1 (NR2C1), transcript variant 1, mRNA
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	603 Amino acids
Molecular weight	67328
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	7181
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 175

HMRbase accession number	21517
Swiss-prot Accession number	B0LPG8 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 3, group C, member 1 (Glucocorticoid receptor) (Nuclear receptor subfamily 3, group C, member 1 (Glucocorticoid receptor), isoform CRA_c)
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	777 Amino acids
Molecular weight	85659
Domain Name	GCR  Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	2908
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 176

HMRbase accession number	21518
Swiss-prot Accession number	B0ZBF5 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 3, group C, member 2 variant 2
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	867 Amino acids
Molecular weight	94373
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 177

HMRbase accession number	21519
Swiss-prot Accession number	B0ZBF6 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 3, group C, member 2 variant 1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	984 Amino acids
Molecular weight	107082
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	4306
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 178

HMRbase accession number	21520
Swiss-prot Accession number	B0ZBF7 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 3, group C, member 2 variant 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	988 Amino acids
Molecular weight	107586
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 179

HMRbase accession number	21521
Swiss-prot Accession number	B0ZBF8 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 3, group C, member 2 variant 4
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	706 Amino acids
Molecular weight	75066
Domain Name	zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 180

HMRbase accession number	21522
Swiss-prot Accession number	Q0VAC9 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 1, group I, member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	314 Amino acids
Molecular weight	35588
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 181

HMRbase accession number	21523
Swiss-prot Accession number	Q147U3 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 5, group A, member 2;Nuclear receptor subfamily 5, group A, member 2, isoform CRA_b
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	495 Amino acids
Molecular weight	56459
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	2494
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 182

HMRbase accession number	21524
Swiss-prot Accession number	Q15626 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 2, group C, member 1;Nuclear receptor subfamily 2, group C, member 1, isoform CRA_b;Steroid receptor (TR2-9)
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	467 Amino acids
Molecular weight	51193
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2597158 2  PubMed abstract 15489334
Hormone	N/A
Gene ID	7181
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 183

HMRbase accession number	21525
Swiss-prot Accession number	Q15627 (Sequence in FASTA format)
Description	TR3beta (Nuclear receptor subfamily 4, group A, member 1, isoform CRA_c) (cDNA, FLJ95235, Homo sapiens nuclear receptor subfamily 4, group A, member 1(NR4A1), transcript variant 3, mRNA)
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	325 Amino acids
Molecular weight	33754
Domain Name	zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 184

HMRbase accession number	21526
Swiss-prot Accession number	Q3KQR7 (Sequence in FASTA format)
Description	NR2F2 protein;cDNA FLJ50900, highly similar to COUP transcription factor 2;Nuclear receptor subfamily 2, group F, member 2, isoform CRA_b
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	281 Amino acids
Molecular weight	31484
Domain Name	Hormone_recep  zf-C4_C
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 185

HMRbase accession number	21527
Swiss-prot Accession number	Q3MSN1 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 3, group C, member 1 (Glucocorticoid receptor); Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	145 Amino acids
Molecular weight	15371
Domain Name	GCR
References	1  PubMed abstract 16216909
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 186

HMRbase accession number	21528
Swiss-prot Accession number	Q3MSN4 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 3, group C, member 1 (Glucocorticoid receptor); Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	145 Amino acids
Molecular weight	15399
Domain Name	GCR
References	1  PubMed abstract 16216909
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 187

HMRbase accession number	21529
Swiss-prot Accession number	Q4U0F0 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 1, group I, member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	357 Amino acids
Molecular weight	40488
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 188

HMRbase accession number	21530
Swiss-prot Accession number	Q4VXA8 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 4, group A, member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	443 Amino acids
Molecular weight	47822
Domain Name	zf-C4
References	----
Hormone	N/A
Gene ID	8013
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 189

HMRbase accession number	21531
Swiss-prot Accession number	Q53EL4 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 4, group A, member 2 isoform a variant; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	598 Amino acids
Molecular weight	66601
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 8125298 2  PubMed abstract 9373149
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 190

HMRbase accession number	21532
Swiss-prot Accession number	Q53RZ2 (Sequence in FASTA format)
Description	Putative uncharacterized protein NR4A2 (Nuclear receptor subfamily 4, group A, member 2, isoform CRA_a)
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	598 Amino acids
Molecular weight	66591
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	4929
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 191

HMRbase accession number	21533
Swiss-prot Accession number	Q53Y00 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 4, group A, member 1;Nuclear receptor subfamily 4, group A, member 1, isoform CRA_d
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	598 Amino acids
Molecular weight	64463
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	3164
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 192

HMRbase accession number	21534
Swiss-prot Accession number	Q59GQ3 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 3, group C, member 2 variant; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	853 Amino acids
Molecular weight	92589
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 193

HMRbase accession number	21535
Swiss-prot Accession number	Q5T6F5 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 5, group A, member 1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	461 Amino acids
Molecular weight	51636
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	2516
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 194

HMRbase accession number	21536
Swiss-prot Accession number	Q5T6F6 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 5, group A, member 1; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	178 Amino acids
Molecular weight	19525
Domain Name	zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 195

HMRbase accession number	21537
Swiss-prot Accession number	Q5T6F7 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 5, group A, member 1; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	245 Amino acids
Molecular weight	28044
Domain Name	Hormone_recep
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 196

HMRbase accession number	21538
Swiss-prot Accession number	Q5U0N9 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 1, group H, member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	447 Amino acids
Molecular weight	50482
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 197

HMRbase accession number	21539
Swiss-prot Accession number	Q5VTW5 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 1, group I, member 3 (Nuclear receptor subfamily 1, group I, member 3, isoform CRA_a)
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	348 Amino acids
Molecular weight	39558
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 198

HMRbase accession number	21540
Swiss-prot Accession number	Q5VTW6 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 1, group I, member 3 (Nuclear receptor subfamily 1, group I, member 3, isoform CRA_b)
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	352 Amino acids
Molecular weight	39942
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 199

HMRbase accession number	21541
Swiss-prot Accession number	Q6GZ85 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV5;Nuclear receptor subfamily 1, group I, member 3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	309 Amino acids
Molecular weight	35043
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709 2  PubMed abstract 15489334
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 200

HMRbase accession number	21542
Swiss-prot Accession number	Q6NXU0 (Sequence in FASTA format)
Description	Nuclear receptor subfamily 4, group A, member 2;cDNA FLJ75035, highly similar to Homo sapiens nuclear receptor subfamily 4, group A, member 2 (NR4A2), transcript variant 4, mRNA
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	535 Amino acids
Molecular weight	59809
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 201

HMRbase accession number	21543
Swiss-prot Accession number	Q6ZMP8 (Sequence in FASTA format)
Description	cDNA FLJ16774 fis, clone BRCAN2019772, highly similar to Orphan nuclear receptor NR2E1;Nuclear receptor subfamily 2, group E, member 1;Nuclear receptor subfamily 2, group E, member 1, isoform CRA_b
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	422 Amino acids
Molecular weight	46400
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 202

HMRbase accession number	21544
Swiss-prot Accession number	Q8IW13 (Sequence in FASTA format)
Description	NR1H3 protein;Nuclear receptor subfamily 1, group H, member 3, isoform CRA_a
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	402 Amino acids
Molecular weight	45692
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	10062
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 203

HMRbase accession number	21634
Swiss-prot Accession number	Q8TDS5 (Sequence in FASTA format)
Description	Oxoeicosanoid receptor 1;Alternative Name: 5-oxo-ETE G-protein coupled receptor;Alternative Name: G-protein coupled receptor TG1019;Alternative Name: G-protein coupled receptor 170;Alternative Name: G-protein coupled receptor R527
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages.
Post translational modification	N/A
Function	Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.
Protein Length	423 Amino acids
Molecular weight	45811
Domain Name	7tm_1
References	1  PubMed abstract 12065583 2  PubMed abstract 12606753 3  PubMed abstract 12044878 4  PubMed abstract 15815621 5  PubMed abstract 15489334
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	165140
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 204

HMRbase accession number	21635
Swiss-prot Accession number	Q15722 (Sequence in FASTA format)
Description	Leukotriene B4 receptor 1;LTB4-R 1;Alternative Name: P2Y purinoceptor 7;P2Y7;Alternative Name: Chemoattractant receptor-like 1;Alternative Name: G-protein coupled receptor 16
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
Post translational modification	Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.
Function	Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Protein Length	352 Amino acids
Molecular weight	37557
Domain Name	7tm_1
References	1  PubMed abstract 8702478 2  PubMed abstract 8558062 3  PubMed abstract 9177352 4  PubMed abstract 8921391 5  PubMed abstract 10934229 6  PubMed abstract 15489334 7  PubMed abstract 12077128
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	1241
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 205

HMRbase accession number	21636
Swiss-prot Accession number	Q9Y271 (Sequence in FASTA format)
Description	Cysteinyl leukotriene receptor 1;CysLTR1;Alternative Name: Cysteinyl leukotriene D4 receptor;LTD4 receptor;Alternative Name: HG55;Alternative Name: HMTMF81
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart.
Post translational modification	N/A
Function	Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Protein Length	337 Amino acids
Molecular weight	38541
Domain Name	7tm_1
References	1  PubMed abstract 10391245 2  PubMed abstract 10462554 3  PubMed abstract 15772651 4  PubMed abstract 15489334
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	10800
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 206

HMRbase accession number	21637
Swiss-prot Accession number	Q9NPC1 (Sequence in FASTA format)
Description	Leukotriene B4 receptor 2;LTB4-R2;Alternative Name: Seven transmembrane receptor BLTR2;Alternative Name: Leukotriene B4 receptor BLT2;Alternative Name: LTB4 receptor JULF2
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Widely expressed.
Post translational modification	N/A
Function	Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
Protein Length	389 Amino acids
Molecular weight	41525
Domain Name	7tm_1
References	1  PubMed abstract 10913346 2  PubMed abstract 10934230 3  PubMed abstract 11006272 4  PubMed abstract 10889186 5  PubMed abstract 12044878
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	56413
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 207

HMRbase accession number	21638
Swiss-prot Accession number	Q9NS75 (Sequence in FASTA format)
Description	Cysteinyl leukotriene receptor 2;CysLTR2;Alternative Name: HG57;Alternative Name: HPN321;Alternative Name: hGPCR21
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Widely expressed, with highest levels in the heart, placenta, spleen, peripheral blood leukocytes and adrenal gland. In lung, expressed in the interstitial macrophages, and slightly in smooth muscle cells.
Post translational modification	N/A
Function	Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
Protein Length	346 Amino acids
Molecular weight	39635
Domain Name	7tm_1
References	1  PubMed abstract 10913337 2  PubMed abstract 10851239 3  PubMed abstract 11093801 4  PubMed abstract 12044878 5  PubMed abstract 15057823 6  PubMed abstract 15489334
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	57105
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 208

HMRbase accession number	21639
Swiss-prot Accession number	P25090 (Sequence in FASTA format)
Description	N-formyl peptide receptor 2;Alternative Name: FMLP-related receptor I;FMLP-R-I;Alternative Name: Formyl peptide receptor-like 1;Alternative Name: Lipoxin A4 receptor;LXA4 receptor;Alternative Name: RFP;Alternative Name: HM63
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis.
Post translational modification	N/A
Function	Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
Protein Length	351 Amino acids
Molecular weight	38964
Domain Name	7tm_1
References	1  PubMed abstract 1612600 2  PubMed abstract 1511907 3  PubMed abstract 1374236 4  PubMed abstract 1373134 5  PubMed abstract 7505609 6  PubMed abstract 9547339 7  PubMed abstract 15057824 8  PubMed abstract 15489334 9  PubMed abstract 9151906
Hormone	Detail in HMRbase
Gene ID	2358
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 209

HMRbase accession number	21640
Swiss-prot Accession number	P43119 (Sequence in FASTA format)
Description	Prostacyclin receptor;Alternative Name: Prostanoid IP receptor;Alternative Name: PGI receptor;Alternative Name: Prostaglandin I2 receptor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling. Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C.
Function	Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
Protein Length	386 Amino acids
Molecular weight	40956
Domain Name	7tm_1
References	1  PubMed abstract 7512962 2  PubMed abstract 7514139 3  PubMed abstract 7923647 4  PubMed abstract 7665161 5  PubMed abstract 15489334 6  PubMed abstract 11895442 7  PubMed abstract 12488443 8  PubMed abstract 15194446
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	5739
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 210

HMRbase accession number	21641
Swiss-prot Accession number	Q13258 (Sequence in FASTA format)
Description	Prostaglandin D2 receptor;Alternative Name: Prostanoid DP receptor;Alternative Name: PGD receptor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed in retina and small intestine.
Post translational modification	N/A
Function	Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate.
Protein Length	359 Amino acids
Molecular weight	40271
Domain Name	7tm_1
References	1  PubMed abstract 7642548 2  PubMed abstract 15489334 3  PubMed abstract 15496624
Hormone	Detail in HMRbase
Gene ID	5729
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 211

HMRbase accession number	21642
Swiss-prot Accession number	P34995 (Sequence in FASTA format)
Description	Prostaglandin E2 receptor EP1 subtype;Alternative Name: Prostanoid EP1 receptor;Alternative Name: PGE receptor, EP1 subtype
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart.
Post translational modification	Phosphorylated (Potential).
Function	Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.
Protein Length	402 Amino acids
Molecular weight	41801
Domain Name	7tm_1
References	1  PubMed abstract 8253813 2  PubMed abstract 15489334
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	5731
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 212

HMRbase accession number	21643
Swiss-prot Accession number	P43116 (Sequence in FASTA format)
Description	Prostaglandin E2 receptor EP2 subtype;Alternative Name: Prostanoid EP2 receptor;Alternative Name: PGE receptor, EP2 subtype
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Placenta and lung.
Post translational modification	N/A
Function	Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
Protein Length	358 Amino acids
Molecular weight	39761
Domain Name	7tm_1
References	1  PubMed abstract 8078484 2  PubMed abstract 10521663 3  PubMed abstract 15489334
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	5732
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 213

HMRbase accession number	21644
Swiss-prot Accession number	P43115 (Sequence in FASTA format)
Description	Prostaglandin E2 receptor EP3 subtype;PGE receptor, EP3 subtype;PGE2-R;Alternative Name: Prostanoid EP3 receptor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels.
Post translational modification	N/A
Function	Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).
Protein Length	390 Amino acids
Molecular weight	43310
Domain Name	7tm_1
References	1  PubMed abstract 8307176 2  PubMed abstract 7883006 3  PubMed abstract 8117308 4  PubMed abstract 8135729 5  PubMed abstract 7981210 6  PubMed abstract 7476918 7  PubMed abstract 8075855 8  PubMed abstract 9073510 9  PubMed abstract 16710414 10  PubMed abstract 15489334 11  PubMed abstract 18023986
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	5733
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 214

HMRbase accession number	21645
Swiss-prot Accession number	P35408 (Sequence in FASTA format)
Description	Prostaglandin E2 receptor EP4 subtype;PGE receptor, EP4 subtype;Alternative Name: Prostanoid EP4 receptor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
Post translational modification	N/A
Function	Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Protein Length	488 Amino acids
Molecular weight	53119
Domain Name	7tm_1
References	1  PubMed abstract 8163486 2  PubMed abstract 8250933 3  PubMed abstract 8661119 4  PubMed abstract 8862514 5  PubMed abstract 15489334 6  PubMed abstract 16424369
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	5734
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 215

HMRbase accession number	21646
Swiss-prot Accession number	P43088 (Sequence in FASTA format)
Description	Prostaglandin F2-alpha receptor;PGF2 alpha receptor;Alternative Name: Prostanoid FP receptor;Alternative Name: PGF receptor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity).
Protein Length	359 Amino acids
Molecular weight	40055
Domain Name	7tm_1
References	1  PubMed abstract 8300593 2  PubMed abstract 9341156 3  PubMed abstract 14702039 4  PubMed abstract 16710414 5  PubMed abstract 15489334
Hormone	Detail in HMRbase
Gene ID	5737
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 216

HMRbase accession number	21647
Swiss-prot Accession number	P21731 (Sequence in FASTA format)
Description	Thromboxane A2 receptor;TXA2-R;Alternative Name: Prostanoid TP receptor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction.
Protein Length	369 Amino acids
Molecular weight	40092
Domain Name	7tm_1
References	1  PubMed abstract 1825698 2  PubMed abstract 8034687 3  PubMed abstract 7896853 4  PubMed abstract 7965765 5  PubMed abstract 8227091 6  PubMed abstract 15057824 7  PubMed abstract 15489334 8  PubMed abstract 8246916 9  PubMed abstract 7929844
Hormone	Detail in HMRbase
Gene ID	N/A
PDB ID	1LBN
Drugpedia	wiki
Comments

Search Result - 217

HMRbase accession number	21648
Swiss-prot Accession number	P46098 (Sequence in FASTA format)
Description	5-hydroxytryptamine receptor 3A;Alternative Name: 5-HT3R;Alternative Name: 5-HT3A;Alternative Name: 5-HT-3;Alternative Name: Serotonin receptor 3A;Alternative Name: Serotonin-gated ion channel receptor; Precursor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the ligand-gated ionic channel (TC 1.A.9) family.
Tissue Specificity	Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta.
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Protein Length	478 Amino acids
Molecular weight	55280
Domain Name	Neur_chan_LBD  Neur_chan_memb
References	1  PubMed abstract 7565620 2  PubMed abstract 8848005 3  PubMed abstract 9928262 4  PubMed abstract 10670426 5  PubMed abstract 15489334 6  PubMed abstract 9950429 7  PubMed abstract 10521471 8  PubMed abstract 12867984 9  PubMed abstract 15809299 10  PubMed abstract 17392525 11  PubMed abstract 15293096 12  PubMed abstract 16487942
Hormone	Detail in HMRbase
Gene ID	3359
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 218

HMRbase accession number	21823
Swiss-prot Accession number	O43245 (Sequence in FASTA format)
Description	Protein p65
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	614 Amino acids
Molecular weight	68620
Domain Name	zf-C4
References	1  PubMed abstract 8706045
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 219

HMRbase accession number	21861
Swiss-prot Accession number	O60587 (Sequence in FASTA format)
Description	Alpha1-fetoprotein transcription factor short variant; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	323 Amino acids
Molecular weight	36410
Domain Name	zf-C4
References	1  PubMed abstract 9858833
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 220

HMRbase accession number	21886
Swiss-prot Accession number	O75780 (Sequence in FASTA format)
Description	Peroxisome proliferator-activated receptor alpha; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	157 Amino acids
Molecular weight	17483
Domain Name	Hormone_recep
References	1  PubMed abstract 7981125 2  PubMed abstract 9610365
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 221

HMRbase accession number	21938
Swiss-prot Accession number	Q06310 (Sequence in FASTA format)
Description	MHC class I promoter binding protein; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	231 Amino acids
Molecular weight	25566
Domain Name	Hormone_recep
References	1  PubMed abstract 1514958
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 222

HMRbase accession number	21940
Swiss-prot Accession number	Q13262 (Sequence in FASTA format)
Description	Oestrogen receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	44 Amino acids
Molecular weight	4604
Domain Name	N/A
References	1  PubMed abstract 8541239
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 223

HMRbase accession number	21941
Swiss-prot Accession number	Q13771 (Sequence in FASTA format)
Description	Androgen receptor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	730 Amino acids
Molecular weight	79150
Domain Name	Androgen_recep  Hormone_recep  zf-C4
References	1  PubMed abstract 2342476
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 224

HMRbase accession number	21942
Swiss-prot Accession number	Q14267 (Sequence in FASTA format)
Description	Estrogen receptor-related protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	336 Amino acids
Molecular weight	37309
Domain Name	Oest_recep  RFX_DNA_binding  zf-C4
References	1  PubMed abstract 1603086
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 225

HMRbase accession number	21943
Swiss-prot Accession number	Q14268 (Sequence in FASTA format)
Description	Estrogen receptor-related protein protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	220 Amino acids
Molecular weight	23936
Domain Name	Oest_recep  zf-C4
References	1  PubMed abstract 1603086
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 226

HMRbase accession number	21944
Swiss-prot Accession number	Q15156 (Sequence in FASTA format)
Description	PML-RAR protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 RING-type zinc finger. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	797 Amino acids
Molecular weight	89282
Domain Name	Hormone_recep  zf-B_box  zf-C4
References	1  PubMed abstract 1652368 2  PubMed abstract 1652369
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 227

HMRbase accession number	21945
Swiss-prot Accession number	Q15625 (Sequence in FASTA format)
Description	Steroid receptor (TR2-11)
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	603 Amino acids
Molecular weight	67300
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2597158
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 228

HMRbase accession number	21946
Swiss-prot Accession number	Q16095 (Sequence in FASTA format)
Description	Estrogen receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	50 Amino acids
Molecular weight	5687
Domain Name	N/A
References	1  PubMed abstract 8275466
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 229

HMRbase accession number	21947
Swiss-prot Accession number	Q16405 (Sequence in FASTA format)
Description	Estrogen receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	12 Amino acids
Molecular weight	1280
Domain Name	N/A
References	1  PubMed abstract 1779972
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 230

HMRbase accession number	22004
Swiss-prot Accession number	Q5QPB7 (Sequence in FASTA format)
Description	Hepatocyte nuclear factor 4, alpha (Hepatocyte nuclear factor 4, alpha, isoform CRA_c)
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	467 Amino acids
Molecular weight	52030
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 231

HMRbase accession number	22018
Swiss-prot Accession number	Q5STQ1 (Sequence in FASTA format)
Description	Retinoid X receptor, beta
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	537 Amino acids
Molecular weight	57365
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 232

HMRbase accession number	22019
Swiss-prot Accession number	Q5TE57 (Sequence in FASTA format)
Description	Hepatocyte nuclear factor 4, alpha; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	100 Amino acids
Molecular weight	11022
Domain Name	zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 233

HMRbase accession number	22068
Swiss-prot Accession number	Q658K5 (Sequence in FASTA format)
Description	Putative uncharacterized protein DKFZp761C0417
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	636 Amino acids
Molecular weight	69540
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 234

HMRbase accession number	22078
Swiss-prot Accession number	Q68CY8 (Sequence in FASTA format)
Description	Putative uncharacterized protein DKFZp686D1580
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	460 Amino acids
Molecular weight	50401
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 235

HMRbase accession number	22084
Swiss-prot Accession number	Q6AW80 (Sequence in FASTA format)
Description	Putative uncharacterized protein DKFZp779O0162; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	156 Amino acids
Molecular weight	17909
Domain Name	zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 236

HMRbase accession number	22100
Swiss-prot Accession number	Q6FGL6 (Sequence in FASTA format)
Description	HNF4G protein; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	408 Amino acids
Molecular weight	45920
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 237

HMRbase accession number	22101
Swiss-prot Accession number	Q6FHY0 (Sequence in FASTA format)
Description	RARB protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	336 Amino acids
Molecular weight	37992
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 238

HMRbase accession number	22107
Swiss-prot Accession number	Q6GZ68 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV22
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	319 Amino acids
Molecular weight	36416
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 239

HMRbase accession number	22108
Swiss-prot Accession number	Q6GZ69 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV21
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	119 Amino acids
Molecular weight	12930
Domain Name	zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 240

HMRbase accession number	22109
Swiss-prot Accession number	Q6GZ70 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV19;Constitutive androstane receptor SV20
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	118 Amino acids
Molecular weight	13460
Domain Name	zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 241

HMRbase accession number	22110
Swiss-prot Accession number	Q6GZ72 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV17;Constitutive androstane receptor SV18
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	147 Amino acids
Molecular weight	16602
Domain Name	zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 242

HMRbase accession number	22111
Swiss-prot Accession number	Q6GZ75 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV15; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	263 Amino acids
Molecular weight	29842
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 243

HMRbase accession number	22112
Swiss-prot Accession number	Q6GZ76 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV14; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	321 Amino acids
Molecular weight	36426
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 244

HMRbase accession number	22113
Swiss-prot Accession number	Q6GZ77 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV13; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	288 Amino acids
Molecular weight	32899
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 245

HMRbase accession number	22114
Swiss-prot Accession number	Q6GZ78 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV12; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	293 Amino acids
Molecular weight	33445
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 246

HMRbase accession number	22115
Swiss-prot Accession number	Q6GZ79 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV11; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	249 Amino acids
Molecular weight	28384
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 247

HMRbase accession number	22116
Swiss-prot Accession number	Q6GZ81 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV10;Constitutive androstane receptor SV4;Constitutive androstane receptor SV9
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	90 Amino acids
Molecular weight	9787
Domain Name	zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 248

HMRbase accession number	22117
Swiss-prot Accession number	Q6GZ82 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV8; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	278 Amino acids
Molecular weight	31526
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 249

HMRbase accession number	22118
Swiss-prot Accession number	Q6GZ83 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV7; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	297 Amino acids
Molecular weight	33829
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 250

HMRbase accession number	22119
Swiss-prot Accession number	Q6GZ84 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV6
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	324 Amino acids
Molecular weight	36961
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 251

HMRbase accession number	22120
Swiss-prot Accession number	Q6GZ87 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV3
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	280 Amino acids
Molecular weight	31900
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 252

HMRbase accession number	22121
Swiss-prot Accession number	Q6GZ89 (Sequence in FASTA format)
Description	Constitutive androstane receptor SV1; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	322 Amino acids
Molecular weight	36587
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15194709
Hormone	N/A
Gene ID	9970
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 253

HMRbase accession number	22126
Swiss-prot Accession number	Q6I9S1 (Sequence in FASTA format)
Description	NR1D2 protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	579 Amino acids
Molecular weight	64655
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 254

HMRbase accession number	22127
Swiss-prot Accession number	Q6IBU6 (Sequence in FASTA format)
Description	NR1H2 protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	461 Amino acids
Molecular weight	51088
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 255

HMRbase accession number	22128
Swiss-prot Accession number	Q6IBU8 (Sequence in FASTA format)
Description	NR4A1 protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	598 Amino acids
Molecular weight	64523
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 256

HMRbase accession number	22131
Swiss-prot Accession number	Q6IPQ7 (Sequence in FASTA format)
Description	NR1H4 protein; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	475 Amino acids
Molecular weight	54605
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 257

HMRbase accession number	22145
Swiss-prot Accession number	Q6LDR0 (Sequence in FASTA format)
Description	Triiodothyronine receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	75 Amino acids
Molecular weight	8994
Domain Name	Hormone_recep
References	1  PubMed abstract 2539258
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 258

HMRbase accession number	22147
Swiss-prot Accession number	Q6MZQ9 (Sequence in FASTA format)
Description	Putative uncharacterized protein DKFZp686N23123
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	310 Amino acids
Molecular weight	35298
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 259

HMRbase accession number	22148
Swiss-prot Accession number	Q6NSM0 (Sequence in FASTA format)
Description	NR1D2 protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	408 Amino acids
Molecular weight	45590
Domain Name	zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 260

HMRbase accession number	22152
Swiss-prot Accession number	Q6P3U7 (Sequence in FASTA format)
Description	RXRA protein; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	516 Amino acids
Molecular weight	56672
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	6256
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 261

HMRbase accession number	22153
Swiss-prot Accession number	Q569H8 (Sequence in FASTA format)
Description	ESRRA protein;Estrogen-related receptor alpha;HCG2016877, isoform CRA_b
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	423 Amino acids
Molecular weight	45510
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	2101
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 262

HMRbase accession number	22159
Swiss-prot Accession number	Q6PHZ7 (Sequence in FASTA format)
Description	NR2C2 protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	530 Amino acids
Molecular weight	57505
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 263

HMRbase accession number	22172
Swiss-prot Accession number	Q6QGY2 (Sequence in FASTA format)
Description	Nuclear receptor AdBP4; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	81 Amino acids
Molecular weight	9481
Domain Name	zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 264

HMRbase accession number	22195
Swiss-prot Accession number	Q6T928 (Sequence in FASTA format)
Description	Vitamin D receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	29 Amino acids
Molecular weight	3339
Domain Name	N/A
References	1  PubMed abstract 16965356
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 265

HMRbase accession number	22200
Swiss-prot Accession number	Q6TZ07 (Sequence in FASTA format)
Description	Progesterone receptor B isoform; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	80 Amino acids
Molecular weight	8229
Domain Name	Prog_receptor
References	----
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 266

HMRbase accession number	22201
Swiss-prot Accession number	Q6TZ08 (Sequence in FASTA format)
Description	Progesterone receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	255 Amino acids
Molecular weight	28727
Domain Name	Hormone_recep  Prog_receptor  zf-C4
References	----
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 267

HMRbase accession number	22223
Swiss-prot Accession number	Q6ZMM6 (Sequence in FASTA format)
Description	cDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor HMR
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	652 Amino acids
Molecular weight	70421
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 268

HMRbase accession number	22255
Swiss-prot Accession number	Q7KYZ0 (Sequence in FASTA format)
Description	P65; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	133 Amino acids
Molecular weight	15100
Domain Name	zf-C4
References	1  PubMed abstract 8706045
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 269

HMRbase accession number	22305
Swiss-prot Accession number	Q7Z2V9 (Sequence in FASTA format)
Description	HNF4G protein;Putative uncharacterized protein DKFZp686E14224
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	408 Amino acids
Molecular weight	45877
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	3174
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 270

HMRbase accession number	22306
Swiss-prot Accession number	Q7Z2W0 (Sequence in FASTA format)
Description	Putative uncharacterized protein DKFZp686P04237
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	482 Amino acids
Molecular weight	55434
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 271

HMRbase accession number	22307
Swiss-prot Accession number	Q7Z5U9 (Sequence in FASTA format)
Description	HNF4G protein; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	80 Amino acids
Molecular weight	9251
Domain Name	zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 272

HMRbase accession number	22404
Swiss-prot Accession number	Q86UC5 (Sequence in FASTA format)
Description	RARB protein; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	346 Amino acids
Molecular weight	39196
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 273

HMRbase accession number	22405
Swiss-prot Accession number	Q86WD1 (Sequence in FASTA format)
Description	CREB3L2-PPARgamma
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	584 Amino acids
Molecular weight	66633
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 274

HMRbase accession number	22440
Swiss-prot Accession number	Q8IVZ9 (Sequence in FASTA format)
Description	NR2E3 protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	322 Amino acids
Molecular weight	35540
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 275

HMRbase accession number	22488
Swiss-prot Accession number	Q8N3V2 (Sequence in FASTA format)
Description	Putative uncharacterized protein DKFZp451G125
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	598 Amino acids
Molecular weight	64446
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 276

HMRbase accession number	22489
Swiss-prot Accession number	Q8N4S8 (Sequence in FASTA format)
Description	Similar to estrogen-related receptor alpha; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	299 Amino acids
Molecular weight	32629
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 277

HMRbase accession number	22490
Swiss-prot Accession number	Q8NG42 (Sequence in FASTA format)
Description	Delta 6/2 progesterone receptor;Progesterone receptor, isoform CRA_a
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	803 Amino acids
Molecular weight	83662
Domain Name	Hormone_recep  Prog_receptor  zf-C4
References	1  PubMed abstract 12673676
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 278

HMRbase accession number	22491
Swiss-prot Accession number	Q8NG43 (Sequence in FASTA format)
Description	Delta4+6/2 progesterone receptor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	690 Amino acids
Molecular weight	71212
Domain Name	Hormone_recep  Prog_receptor  zf-C4
References	1  PubMed abstract 12673676
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 279

HMRbase accession number	22492
Swiss-prot Accession number	Q8NG44 (Sequence in FASTA format)
Description	Delta 3+6/2 progesterone receptor;Progesterone receptor, isoform CRA_e
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	764 Amino acids
Molecular weight	79315
Domain Name	Hormone_recep  Prog_receptor  zf-C4
References	1  PubMed abstract 12673676
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 280

HMRbase accession number	22493
Swiss-prot Accession number	Q8NG45 (Sequence in FASTA format)
Description	Progesterone receptor;Progesterone receptor, isoform CRA_f
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	695 Amino acids
Molecular weight	71728
Domain Name	Hormone_recep  Prog_receptor  zf-C4
References	1  PubMed abstract 12579263
Hormone	Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 281

HMRbase accession number	22521
Swiss-prot Accession number	Q8TDS3 (Sequence in FASTA format)
Description	Delta 4 progesterone receptor;Progesterone receptor, isoform CRA_c
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	831 Amino acids
Molecular weight	87747
Domain Name	Hormone_recep  Prog_receptor  zf-C4
References	1  PubMed abstract 9598870
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 282

HMRbase accession number	22551
Swiss-prot Accession number	Q8WY08 (Sequence in FASTA format)
Description	Nuclear receptor NR5A2; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	21 Amino acids
Molecular weight	2230
Domain Name	N/A
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 283

HMRbase accession number	22680
Swiss-prot Accession number	Q96F89 (Sequence in FASTA format)
Description	Putative uncharacterized protein; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	55 Amino acids
Molecular weight	6118
Domain Name	Hormone_recep
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 284

HMRbase accession number	22681
Swiss-prot Accession number	Q96I02 (Sequence in FASTA format)
Description	ESRRA protein; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	320 Amino acids
Molecular weight	35027
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15489334
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 285

HMRbase accession number	22711
Swiss-prot Accession number	Q9BZG5 (Sequence in FASTA format)
Description	Androgen receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	531 Amino acids
Molecular weight	54419
Domain Name	Androgen_recep
References	1  PubMed abstract 12124798
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 286

HMRbase accession number	22712
Swiss-prot Accession number	Q9BZG6 (Sequence in FASTA format)
Description	Androgen receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	542 Amino acids
Molecular weight	55828
Domain Name	Androgen_recep
References	1  PubMed abstract 12124798
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 287

HMRbase accession number	22713
Swiss-prot Accession number	Q9BZG7 (Sequence in FASTA format)
Description	Androgen receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	544 Amino acids
Molecular weight	56013
Domain Name	Androgen_recep
References	1  PubMed abstract 12124798
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 288

HMRbase accession number	22714
Swiss-prot Accession number	Q9BZI0 (Sequence in FASTA format)
Description	Retinoic acid receptor gamma; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	102 Amino acids
Molecular weight	11212
Domain Name	Hormone_recep
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 289

HMRbase accession number	22785
Swiss-prot Accession number	Q9H1Z6 (Sequence in FASTA format)
Description	Estrogen receptor 1; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	12 Amino acids
Molecular weight	1385
Domain Name	N/A
References	----
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 290

HMRbase accession number	22786
Swiss-prot Accession number	Q9H2M1 (Sequence in FASTA format)
Description	Estrogen receptor alpha;Estrogen receptor 1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	334 Amino acids
Molecular weight	36685
Domain Name	Hormone_recep  Oest_recep
References	1  PubMed abstract 11004670
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 291

HMRbase accession number	22787
Swiss-prot Accession number	Q9H2M2 (Sequence in FASTA format)
Description	Estrogen receptor alpha
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	152 Amino acids
Molecular weight	16308
Domain Name	Oest_recep
References	1  PubMed abstract 11004670
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 292

HMRbase accession number	22788
Swiss-prot Accession number	Q9H3V4 (Sequence in FASTA format)
Description	Ad4BP; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	34 Amino acids
Molecular weight	3852
Domain Name	zf-C4
References	1  PubMed abstract 11071856
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 293

HMRbase accession number	22789
Swiss-prot Accession number	Q9HCB2 (Sequence in FASTA format)
Description	HERRB2; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	262 Amino acids
Molecular weight	28204
Domain Name	zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 294

HMRbase accession number	22839
Swiss-prot Accession number	Q9NUA2 (Sequence in FASTA format)
Description	Androgen receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	539 Amino acids
Molecular weight	55444
Domain Name	Androgen_recep
References	1  PubMed abstract 12124798
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 295

HMRbase accession number	22899
Swiss-prot Accession number	Q9UBT1 (Sequence in FASTA format)
Description	Estrogen receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	23 Amino acids
Molecular weight	2526
Domain Name	Oest_recep
References	1  PubMed abstract 3753802 2  PubMed abstract 3754034 3  PubMed abstract 2015052 4  PubMed abstract 1567414 5  PubMed abstract 1476547 6  PubMed abstract 8240974 7  PubMed abstract 8647321 8  PubMed abstract 9393949
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	2099
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 296

HMRbase accession number	22900
Swiss-prot Accession number	Q9UCY6 (Sequence in FASTA format)
Description	Orphan nuclear receptor steroidogenic factor 1, SF-1(long terminal repeat-binding protein, ELP)
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	205 Amino acids
Molecular weight	22289
Domain Name	zf-C4
References	1  PubMed abstract 7479914
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 297

HMRbase accession number	22901
Swiss-prot Accession number	Q9UD41 (Sequence in FASTA format)
Description	Beta-isoform thyroid hormone receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	16 Amino acids
Molecular weight	1920
Domain Name	N/A
References	1  PubMed abstract 7528740
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 298

HMRbase accession number	22902
Swiss-prot Accession number	Q9UD95 (Sequence in FASTA format)
Description	Androgen receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	68 Amino acids
Molecular weight	7577
Domain Name	zf-C4
References	1  PubMed abstract 8413310
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 299

HMRbase accession number	22903
Swiss-prot Accession number	Q9UE35 (Sequence in FASTA format)
Description	Estrogen receptor protein (Estrogen receptor 1); Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	115 Amino acids
Molecular weight	12088
Domain Name	Oest_recep
References	1  PubMed abstract 3754034 2  PubMed abstract 3145193 3  PubMed abstract 1476547
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 300

HMRbase accession number	22904
Swiss-prot Accession number	Q9UEC0 (Sequence in FASTA format)
Description	FTZ-F1 related protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	541 Amino acids
Molecular weight	61321
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 301

HMRbase accession number	22905
Swiss-prot Accession number	Q9UKJ6 (Sequence in FASTA format)
Description	Androgen receptor; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	9 Amino acids
Molecular weight	1272
Domain Name	N/A
References	----
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 302

HMRbase accession number	22906
Swiss-prot Accession number	Q9UN21 (Sequence in FASTA format)
Description	Androgen receptor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	906 Amino acids
Molecular weight	97885
Domain Name	Androgen_recep  Hormone_recep  zf-C4
References	----
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 303

HMRbase accession number	22947
Swiss-prot Accession number	Q9Y2W8 (Sequence in FASTA format)
Description	Alternatively-spliced estrogen receptor alpha; Fragment
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	113 Amino acids
Molecular weight	12635
Domain Name	N/A
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 304

HMRbase accession number	22953
Swiss-prot Accession number	P48357 (Sequence in FASTA format)
Description	Leptin receptor;LEP-R;Alternative Name: OB receptor;OB-R;Alternative Name: HuB219;Alternative Name: CD_antigen=CD295;Precursor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Cell membrane; Single-pass type I membrane protein. Isoform E: Secreted (Probable)
Developmental Stage	N/A
Similarity	Belongs to the type I cytokine receptor family. Type 2 subfamily. Contains 4 fibronectin type-III domains. Contains 1 Ig-like (immunoglobulin-like) domain.
Tissue Specificity	Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.
Post translational modification	On ligand binding, phosphorylated on two conserved C-terminal tyrosine residues (isoform B only) by JAK2. Tyr-986 is required for complete binding and activation of PTPN11, ERK/FOS activation and, for interaction with SOCS3 (By similarity). Phosphorylation on Tyr-1141 is required for STAT3 binding/activation.
Function	Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).
Protein Length	1165 Amino acids
Molecular weight	132494
Domain Name	fn3  Lep_receptor_Ig
References	1  PubMed abstract 8548812 2  PubMed abstract 8805376 3  PubMed abstract 8616721 4  PubMed abstract 9158141 5  PubMed abstract 9061609 6  PubMed abstract 9929394 7  PubMed abstract 9600917 8  PubMed abstract 9786864 9  PubMed abstract 16335952 10  PubMed abstract 8666155 11  PubMed abstract 9144432 12  PubMed abstract 9287054 13  PubMed abstract 9175732 14  PubMed abstract 9860295 15  PubMed abstract 18987736
Hormone	P41159   Detail in HMRbase    A4D0Y8   Detail in HMRbase    B2R8Y2   Detail in HMRbase    Q6NT58   Detail in HMRbase
Gene ID	3953
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 305

HMRbase accession number	22959
Swiss-prot Accession number	O95214 (Sequence in FASTA format)
Description	Leptin receptor overlapping transcript-like 1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; Multi-pass membrane protein (Potential)
Developmental Stage	N/A
Similarity	Belongs to the OB-RGRP/VPS55 family.
Tissue Specificity	Widely expressed, with highest expression in heart, testis, adrenal gland, thymus, and spleen, and lowest expression in lung and skeletal muscle.
Post translational modification	N/A
Function	N/A
Protein Length	131 Amino acids
Molecular weight	14428
Domain Name	Vps55
References	1  PubMed abstract 11342119 2  PubMed abstract 12975309 3  PubMed abstract 15489334
Hormone	P41159   Detail in HMRbase    A4D0Y8   Detail in HMRbase    B2R8Y2   Detail in HMRbase    Q6NT58   Detail in HMRbase
Gene ID	23484
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 306

HMRbase accession number	22962
Swiss-prot Accession number	O15243 (Sequence in FASTA format)
Description	Leptin receptor gene-related protein;Alternative Name: OB-R gene-related protein;OB-RGRP;Alternative Name: Leptin receptor overlapping transcript protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; Multi-pass membrane protein (Potential)
Developmental Stage	N/A
Similarity	Belongs to the OB-RGRP/VPS55 family.
Tissue Specificity	Expressed at the highest levels in heart and placenta and at a lesser extent in lung, liver, skeletal muscle, kidney and pancreas.
Post translational modification	N/A
Function	N/A
Protein Length	131 Amino acids
Molecular weight	14254
Domain Name	Vps55
References	1  PubMed abstract 9207021 2  PubMed abstract 15489334
Hormone	P41159   Detail in HMRbase    A4D0Y8   Detail in HMRbase    B2R8Y2   Detail in HMRbase    Q6NT58   Detail in HMRbase
Gene ID	54741
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 307

HMRbase accession number	22966
Swiss-prot Accession number	A8K2E3 (Sequence in FASTA format)
Description	cDNA FLJ77491, highly similar to Homo sapiens leptin receptor (LEPR), transcript variant 2, mRNA
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	896 Amino acids
Molecular weight	102492
Domain Name	fn3  Lep_receptor_Ig
References	----
Hormone	P41159   Detail in HMRbase    A4D0Y8   Detail in HMRbase    B2R8Y2   Detail in HMRbase    Q6NT58   Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 308

HMRbase accession number	22967
Swiss-prot Accession number	Q6FHL5 (Sequence in FASTA format)
Description	LEPR protein;HCG20174, isoform CRA_a;cDNA FLJ90360 fis, clone NT2RP2003664, highly similar to Leptin receptor gene-related protein
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	131 Amino acids
Molecular weight	14254
Domain Name	Vps55
References	1  PubMed abstract 16303743
Hormone	P41159   Detail in HMRbase    A4D0Y8   Detail in HMRbase    B2R8Y2   Detail in HMRbase    Q6NT58   Detail in HMRbase
Gene ID	54741
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 309

HMRbase accession number	22968
Swiss-prot Accession number	Q6FHL7 (Sequence in FASTA format)
Description	LEPROTL1 protein;Transformation-related protein 12;Leptin receptor overlapping transcript-like 1, isoform CRA_b;cDNA PSEC0049 fis, clone NT2RP2000116, highly similar to Leptin receptor overlapping transcript-like 1
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	131 Amino acids
Molecular weight	14428
Domain Name	Vps55
References	1  PubMed abstract 16303743
Hormone	P41159   Detail in HMRbase    A4D0Y8   Detail in HMRbase    B2R8Y2   Detail in HMRbase    Q6NT58   Detail in HMRbase
Gene ID	23484
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 310

HMRbase accession number	22992
Swiss-prot Accession number	O75787 (Sequence in FASTA format)
Description	Renin receptor;Alternative Name: Renin/prorenin receptor;Alternative Name: ATPase H(+)-transporting lysosomal accessory protein 2;Alternative Name: ATPase H(+)-transporting lysosomal-interacting protein 2;Alternative Name: Vacuolar ATP synthase membrane sector-associated protein M8-9;Short=V-ATPase M8.9 subunit;Alternative Name: ATP6M8-9;Alternative Name: N14F;Alternative Name: ER-localized type I transmembrane adaptor;Alternative Name: Embryonic liver differentiation factor 10;Precursor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; Single-pass type I membrane protein (Potential)
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncitiotrophoblast cells in the mature fetal placenta.
Post translational modification	Phosphorylated.
Function	Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).
Protein Length	350 Amino acids
Molecular weight	39008
Domain Name	Renin_r
References	1  PubMed abstract 12045255 2  PubMed abstract 10931946 3  PubMed abstract 15489334 4  PubMed abstract 9556572 5  PubMed abstract 15746149
Hormone	P00797   Detail in HMRbase    Q6FI38   Detail in HMRbase
Gene ID	10159
PDB ID	N/A
Drugpedia	wiki
Comments